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Surgical Sealants and Adhesives Market

The market for Surgical Sealants and Adhesives was estimated at $2.8 billion in 2025; it is anticipated to increase to $4.2 billion by 2030, with projections indicating growth to around $6.4 billion by 2035.

Report ID:DS1806005
Author:Debadatta Patel - Senior Consultant
Published Date:
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Life Science
Other Healthcare
Surgical Sealants and Adhesives
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Market Data
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Global Surgical Sealants and Adhesives Market Outlook

Revenue, 2025

$2.8B

Forecast, 2035

$6.4B

CAGR, 2026 - 2035

8.5%

The Surgical Sealants and Adhesives industry revenue is expected to be around $2.8 billion in 2026 and expected to showcase growth with 8.5% CAGR between 2026 and 2035. The positive perspective shows how Surgical Sealants and Adhesives function as essential tools in contemporary operating rooms because medical staff focus on quick wound closure and strong tissue adhesion and minimal post surgical issues which affect multiple medical fields. The market shows its highest interest in general surgery and cardiac surgery because these two fields combined represent 50.4% of worldwide application demand. The two fields demonstrate how their high acuity procedures need sophisticated tissue sealants to stop bleeding and block fluid or air from escaping. The market for natural/biological sealants reached $1.9 billion in 2025 because surgeons choose these products because they are biocompatible and resorbable and they help achieve better medical results which support value based care and enhanced recovery protocols.

Surgical Sealants and Adhesives include various natural/biological and synthetic polymer based adhesives which provide fast blood clotting and strong tissue bonding and adaptable barriers that match the properties of surrounding tissues. These solutions function as alternatives to sutures and staples during general surgery and cardiac surgery and orthopedic and neurosurgical and minimally invasive procedures which results in shorter surgical durations and decreased blood transfusions and lower chances of needing additional surgery. The current market trends which affect demand development include the creation of sprayable and preloaded applicator systems and new biomaterials which target particular organ systems and surgical products designed for robotic and image guided procedures. The market adoption of high performance Surgical Sealants and Adhesives in hospitals and ambulatory surgical centers continues to grow because of these new products.

Surgical Sealants and Adhesives market outlook with forecast trends, drivers, opportunities, supply chain, and competition 2025-2035
Surgical Sealants and Adhesives Market Outlook

Market Key Insights

  • The Surgical Sealants And Adhesives market is projected to grow from $2.8 billion in 2025 to $6.4 billion in 2035. This represents a CAGR of 8.5%, reflecting rising demand across General Surgery, Cardiac Surgery, and Pulmonary Surgery.

  • Baxter International Inc. and Johnson & Johnson and Medtronic Plc lead the market through their position as leading competitors who determine its competitive structure.

  • The Surgical Sealants And Adhesives market shows its highest demand through the United States and Germany which will experience CAGR growth rates of 6.2% to 8.9% during 2025 to 2030.

  • The research predicts that India, Brazil and Mexico will experience the most significant market expansion at rates between 8.2% and 10.6% CAGR.

  • The Surgical Sealants And Adhesives market will experience $328 million worth of growth during 2030 because of expected developments in Bioengineering transition.

  • The Surgical Sealants And Adhesives market will experience a $3.6 billion expansion from 2025 to 2035 while manufacturers focus on developing Cardiac Surgery & Pulmonary Surgery Application for increased market dominance.

  • With

    advancements in surgical techniques, and

    Rising Disease Incidences, Surgical Sealants And Adhesives market to expand 126% between 2025 and 2035.

surgical sealants and adhesives market size with pie charts of major and emerging country share, CAGR, trends for 2025 and 2032
Surgical Sealants and Adhesives - Country Share Analysis

Opportunities in the Surgical Sealants and Adhesives

North American hospitals focus on quick patient recovery and minimal surgical entry points and decreased blood transfusion requirements which drives them to use synthetic and semi synthetic Surgical Sealants and Adhesives for minimally invasive and robotic procedures. The global market for this segment currently generates 0.92 billion dollars in 2025 and experts predict it will also expand to 1.42 billion dollars by 2030 with an 8.91% annual growth rate. The market will focus on sophisticated hemostatic sealants and tissue adhesives which work together with surgical robots and energy based wound closure devices.

Growth Opportunities in North America and Asia-Pacific

The North American market for Surgical Sealants and Adhesives shows its highest adoption rate in Cardiac Surgery because this field performs numerous complex cardiovascular procedures through minimally invasive methods which require surgical hemostats and fibrin based adhesives for operating room success. The company should focus on developing high end wound closure solutions which use scientific evidence to support their use for patients undergoing dangerous heart and chest surgeries and on creating surgical wound treatments for laparoscopic operations and cardiovascular device integration. The competition between established multinational companies and agile niche innovators who use bioabsorbable polymers and complication reduction data to secure value based hospital procurement contracts determines market competition. The market has three main factors which drive its development through hospitals that enforce strict safety standards and hospital network consolidation and medical organizations that support Surgical Sealants and Adhesives which combine multiple functions with user friendly design and demonstrate solid health benefits for patients.
The Asia Pacific region demonstrates the highest importance of Surgical Sealants and Adhesives in General Surgery because of rising procedure numbers and developing surgical facilities and better healthcare services for basic and advanced medical procedures in both government and private healthcare facilities. The main business opportunity exists for surgical hemostats and wound closure products which offer versatility at affordable prices to perform general surgery procedures through open and minimally invasive methods before they can enter Orthopaedic Surgery and Pulmonary Surgery markets when reimbursement systems become more established. The market competition between regional manufacturers and contract formulators forces global brands to establish local production facilities while they need to modify their packaging sizes and work together to create surgical and orthopaedic implant compatible formulations. The main factors which drive the core region forward consist of increasing healthcare costs and medical tourism activities and official backing for sophisticated operating theater equipment and surgeons who choose dependable Surgical Sealants and Adhesives for their operations. The market will focus on middle range price points and establish distribution networks and educational programs for surgeons because of these regional factors.

Market Dynamics and Supply Chain

01

Driver: Rising Minimally Invasive Surgeries Coupled with Technological Advancements in Bioadhesives

The surge in minimally invasive procedures is also driving demand for surgical sealants and adhesives. These surgeries, including laparoscopic and robotic-assisted interventions, require materials that can also ensure rapid hemostasis, tissue approximation, and reduced post-operative complications. Simultaneously, innovations in bioadhesive formulations, such as synthetic polymers and fibrin-based sealants, enhance tissue compatibility, faster setting times, and improved tensile strength. Together, these factors enable surgeons to perform complex procedures with higher precision and lower complication rates. The intersection of procedural growth and material innovation is also particularly evident in cardiovascular, orthopedic, and gastrointestinal surgeries, where rapid wound closure and reduced infection risks are also critical. Companies investing in next-generation adhesives are also capitalizing on both operational efficiency and improved patient outcomes, reflecting a dual push in adoption across advanced hospital networks globally.
High-risk surgeries, such as cardiac, neurosurgical, and liver transplant procedures, are also increasingly relying on advanced hemostatic sealants to minimize bleeding complications. These adhesives offer superior biocompatibility and rapid coagulation, reducing the need for transfusions and extended operative time. Technological improvements in polymer chemistry and fibrinogen-thrombin formulations are also enhancing efficacy, driving adoption among specialty surgeons, and positioning sealants as indispensable in high-stakes surgical environments.
02

Restraint: High Product Costs and Limited Reimbursement Undermine Adoption in Cost‑Sensitive Markets

The high cost of advanced surgical sealants and adhesives, particularly bio‑based or synthetic formulations, remains a major restraint that limits broader market penetration, especially in developing healthcare systems with constrained budgets. Premium sealants often cost significantly more than traditional sutures and staples, discouraging purchasing in price‑sensitive hospitals and ambulatory centers, which directly suppresses market revenue and demand growth. Additionally, limited reimbursement coverage for these products in many regions shifts cost burdens to providers or patients, further hindering adoption and slowing overall market expansion across diverse clinical applications. 
03

Opportunity: Innovative bioabsorbable, drug-eluting sealants for chronic wound management in Europe offer high-margin opportunities and Aging populations and cardiovascular surgeries in Asia-Pacific create strong demand for natural surgical sealants

The high occurrence of diabetes and vascular disease and pressure ulcers throughout Europe has created a need for advanced Surgical Sealants and Adhesives which specifically address chronic wound treatment. The market contains unexplored opportunities for bioabsorbable drug eluting tissue adhesives which can be used in outpatient clinics and home based patient care settings. Companies which merge regenerative medicine elements with antimicrobial release functions and negative pressure system compatibility will achieve higher market value. The market will experience its most significant expansion through the development of natural and synthetic hybrid formulations which will find their highest demand in Western European countries that want to minimize hospital readmissions and decrease patient hospitalization duration.
The Asia Pacific region experiences rising numbers of cardiac bypass procedures and valve repair operations and orthopedic reconstruction surgeries which creates opportunities for natural and biological Surgical Sealants and Adhesives that match medical staff choices for biocompatible materials. The worldwide market for this product segment will expand from 1.90 billion dollars to 2.82 billion dollars during 2025 2030 with an 8.3% annual growth rate while China and India and Southeast Asia will lead the market adoption. The market for bioabsorbable polymers and biologically derived hemostatic sealants will experience its highest growth rate in tertiary hospitals and cardiac centers.
04

Challenge: Stringent Regulatory Approvals and Safety Concerns Delay Innovation and Market Entry

The complex and lengthy regulatory approval processes required by authorities like the FDA and EMA pose a significant challenge for manufacturers of surgical sealants and adhesives, delaying time‑to‑market for innovative products and increasing development costs. These regulatory hurdles can extend approval timelines by years, reducing competitive agility and limiting the introduction of new, high‑performance materials. At the same time, concerns about product safety and efficacy, including adverse reactions or bio‑compatibility issues, can reduce clinician confidence and slow clinical adoption, negatively impacting overall market dynamics and revenue growth.

Supply Chain Landscape

1

Raw Materials Supply

3M CompanyB. Braun Melsungen AG
2

Surgical Sealants and Adhesives

Baxter International Inc.Johnson & JohnsonMedtronic Plc
3

Packaging & Distribution

CryoLife Inc.C.R. Bard Inc
4

Clinical End Users

HospitalsAmbulatory Surgical CentersSpecialty Clinics
Surgical Sealants and Adhesives - Supply Chain

Use Cases of Surgical Sealants and Adhesives in General Surgery & Cardiac Surgery

General Surgery : In general surgery, surgical sealants and adhesives such as fibrin-based biological sealants, cyanoacrylate adhesives, and synthetic/semi-synthetic tissue sealants are widely used by hospitals and surgical centers to reinforce wound closure, promote hemostasis and reduce leakage in procedures like hernia repair, gastrointestinal resections and complex soft-tissue surgeries. These products offer advantages over traditional sutures by enhancing healing and minimizing bleeding risks. Leading players like Johnson & Johnson’s Ethicon, Baxter International, B. Braun Melsungen and Medtronic hold strong positions with broad portfolios and global distribution, supported by ongoing innovation in biocompatible formulations and strong clinical adoption. General surgery remains the largest application segment globally, reflecting high surgical volumes and demand for reliable wound-closure solutions.
Cardiac Surgery : Cardiac surgery increasingly relies on biological and fibrin-based surgical sealants and adhesives to control bleeding and ensure secure tissue closure. Cardiothoracic surgeons in hospitals use these materials during procedures such as valve repair, coronary artery bypass, and vascular grafting to reduce blood loss, minimize leakage, and lower postoperative complications. Leading companies like Johnson & Johnson’s Ethicon, Baxter International, and Medtronic provide advanced hemostatic sealants with strong clinical support and broad distribution, reinforcing their market leadership and driving adoption in complex cardiac interventions.
Pulmonary Surgery : In pulmonary surgery, surgical sealants and adhesives such as fibrin‑based sealants and synthetic hydrogel sealants are widely used by thoracic surgeons in hospitals to seal air leaks and reinforce lung tissue after resection, significantly reducing postoperative complications like alveolar leaks and shortening chest drain duration. Fibrin sealants offer excellent biocompatibility and hemostasis, while hydrogel products provide flexible, airtight closure of visceral pleural defects. Leading providers such as Johnson & Johnson, Baxter International, and Becton Dickinson hold strong market positions with broad portfolios and clinical support, while mid‑tier innovators focus on next‑generation bioadhesive formulations that improve adhesion in the dynamic pulmonary environment.

Recent Developments

Recent strategic developments in the surgical sealants and adhesives market highlight product innovation and expanded accessibility as major themes. Baxter’s launch of its room‑temperature Hemopatch sealing hemostat improves usability in both open and minimally invasive surgery, addressing cold‑chain challenges and enhancing operating‑room efficiency. This aligns with a broader trend toward advanced biomaterials and synthetic bioadhesives that provide stronger tissue bonding and faster hemostasis. Growing adoption of next‑generation bio‑based sealants in cardiovascular, thoracic, and general surgeries underscores continued investment in R&D and biocompatible adhesive technologies by leading manufacturers.

June 2025 : Baxter International Inc. introduced an updated Hemopatch sealing hemostat optimized for room‑temperature storage and deployment in European markets, enhancing convenience and operational efficiency in vascular and general surgery. This product expansion strengthens Baxter’s portfolio of surgical sealants with improved usability and broader clinical adoption. 
March 2024 : Medtronic Plc launched its VISTASEAL fibrin sealant in the Japanese market for surgical bleeding control, extending the company’s geographic footprint and offering surgeons additional biologic sealing options in Asia.
June 2024 : Johnson & Johnson’s introduced its next‑generation SURGICEL Powder absorbable hemostat across European markets to enhance bleeding control during surgery, reinforcing Ethicon’s leadership in advanced hemostatic and adhesive products.

Impact of Industry Transitions on the Surgical Sealants and Adhesives Market

As a core segment of the Other Healthcare industry, the Surgical Sealants and Adhesives market develops in line with broader industry shifts. Over recent years, transitions such as Advancements in Bioengineering and Integration with Minimally Invasive Techniques have redefined priorities across the Other Healthcare sector, influencing how the Surgical Sealants and Adhesives market evolves in terms of demand, applications and competitive dynamics. These transitions highlight the structural changes shaping long-term growth opportunities.
01

Advancements in Bioengineering

The Surgical Sealants and Adhesives market experiences its main growth acceleration through bioengineering developments which will generate $328 million additional market value during 2030. The development of next generation bioengineered surgical adhesives and tissue compatible sealants which use biocompatible materials and biodegradable polymers has brought better safety results and decreased postoperative issues which lead to improved medical results for complex wound closure systems. The changing medical landscape supports this transition because minimally invasive surgery now dominates healthcare practices which need fast and dependable sealing systems. The development of advanced hemostatic agents and regenerative medicine formulations enables manufacturers to create specialized Surgical Sealants and Adhesives products which target particular tissues and surgical methods thus strengthening their market position and creating new lucrative region's in the worldwide surgical sealants industry.
02

Integration with Minimally Invasive Techniques

Another significant transition is the integration of surgical sealants and adhesives with minimally invasive procedures. Advanced sealants are now designed for laparoscopic, thoracoscopic, and robotic-assisted surgeries, where small incisions limit manual suturing capabilities. For example, in pulmonary and gastrointestinal interventions, these adhesives facilitate faster, safer closure of tissues in confined operative spaces, improving patient recovery and reducing hospital stay. This trend positively impacts the robotic surgery and endoscopic device sectors, prompting device manufacturers to develop compatible sealant delivery systems and expanding the clinical adoption of advanced tissue adhesives.