Cryo EM Market
Cryo EM Market
The market for Cryo EM was estimated at $1.32 billion in 2024; it is anticipated to increase to $2.6 billion by 2030, with projections indicating growth to around $4.7 billion by 2035.
Report Summary
Table of Contents
Methodology
Market Data
Global Cryo EM Market Outlook
Revenue, 2024 (US$B)
$1.3B
Forecast, 2034 (US$B)
$4.2B
CAGR, 2024 - 2034
12.2%
The Cryo EM industry revenue is expected to be around $1.5 billion in 2025 and expected to showcase growth with 12.2% CAGR between 2025 and 2034. <p>The Cryogenic Electron Microscopy ( CryoEM or cryogenic transmission electron microscopy / cryotransmission electron microscopy - CryoTEM) market is witnessing notable expansion due to the rising need for detailed imaging in the fields of structural biology and pharmaceutical research and development (R&D). In 2024 the market was valued at USD 1.3 billion with an estimated compound annual growth rate of 12.2% and projected to reach USD 2.6 billion by 2030 and USD 4.7 billion by 2035. The Cryogenic electron microscopy allows for the visualization of molecules in their natural states with exceptional clarity at the atomic level near native states on an atomic scale and has brought about a significant transformation, in structural biology and pharmaceutical product development.</p><p>Advancements in technology are being utilized in sectors such as molecular research and materials science to drive progress in comprehending protein structures and virus mechanisms as well as cellular processes. Cryo Electron Microscopy (Cryo–EM) is within reach for pharmaceutical companies,research institutions and academic centers due, to improved detector technology and automation.</p>
Market Key Insights
- The Cryo EM market is projected to grow from $1.3 billion in 2024 to $4.2 billion in 2034. This represents a CAGR of 12.2%, reflecting rising demand across Structural Biology, Materials Science and Drug Discovery.
- <p>Thermo Fisher Scientific, Danaher, JEOL are among the leading players in this market, shaping its competitive landscape.</p>
- U.S. and Japan are the top markets within the Cryo EM market and are expected to observe the growth CAGR of 11.0% to 14.6% between 2024 and 2030.
- Emerging markets including India, South Korea and Brazil are expected to observe highest growth with CAGR ranging between 8.5% to 12.8%.
- <p>Transition like Transition to Cost-Effective Cryo-EM Solutions is expected to add $400.0 million to the Cryo Em market growth by 2030</p>
- The Cryo EM market is set to add $2.9 billion between 2024 and 2034, with manufacturer targeting Life Science Research & Academia & Healthcare/Medical Applications Application projected to gain a larger market share.
- With Increasing adoption in structural biology, and Advancements in detector and imaging technologies, Cryo EM market to expand 216% between 2024 and 2034.
Opportunities in the Cryo EM
Integrating AI into Cryo‐EM enables image analysis and cuts down on processing time.
Growth Opportunities in North America and Asia-Pacific
North America Outlook
<p>In North Americas Cryo‐EM market stands out as a player due to significant research and development efforts in the biopharmaceutical and structural biology sectors.Through their offerings of Cryogenic Electron Microscopy systems specifically designed for this market Thermo Fisher Scientific and JEOL are key players, in driving innovation in this field.</p>
Asia-Pacific Outlook
<p>In the Asia Pacific region. In China and Japan. There is a notable increase in the use of Cryogenic Electron Microscopy (Cryo EM) due to the escalating investments in life sciences field. Companies from both international markets are expanding their operations to cater to the increasing need for advanced imaging technology, in the region.</p>
Market Dynamics and Supply Chain
01
Driver: Increasing Adoption in Structural Biology, and Rising Demand in Drug Discovery
The use of cryogenic electron microscopy (Cryo‐EM) to uncover protein structures is also fuel the uptake in molecular biology and structural analysis. Cryo electron microscopy plays a role in helping researchers visualize the interactions between drugs and their targets. This technology speeds up the drug discovery process. Contributes to the expansion of the market, in this field.<br>Advancements in detector technology and automation are also enhancing the clarity and speed of data collection in Cryo‐EM.
02
Restraint: High Cost of Cryo-EM Systems, and High Cost of Cryo-EM Systems
The significant cost involved in acquiring Cryogenic Electron Microscopy systems poses a barrier to entry, for institutions.<br>The significant cost involved in acquiring Cryogenic Electron Microscopy systems poses a barrier to entry, for institutions.
03
Opportunity: Expansion in Developing Regions and Development of Compact and Cost-Effective Systems
The increasing number of research facilities in developing economies is driving the need, for Cryogenic Electron Microscopy systems.<br>Innovative advancements, in Cryogenic Electron Microscopy technology are now enabling smaller laboratories to access this cutting edge solution.
04
Challenge: Technical Complexity and Skilled Personnel Requirement
Using Cryogenic Electron Microscopy necessitates individuals to operate it effectively. This poses a challenge, to its use.
Supply Chain Landscape
1
Sample Preparation Kit Supplier
Thermo Fisher Scientific
Leica Microsystems
2
Microscope Manufacturer
JEOL
Hitachi
3
Distributor
VWR
Avantor
4
End User
Pharmaceutical companies
Academic institutions
Biotechnology firms
1
Sample Preparation Kit Supplier
Thermo Fisher Scientific
Leica Microsystems
2
Microscope Manufacturer
JEOL
Hitachi
3
Distributor
VWR
Avantor
4
End User
Pharmaceutical companies
Academic institutions
Biotechnology firms
*The illustration highlights the key stakeholders within the supply chain ecosystem.
Applications of Cryo EM in Structural Biology, Materials Science & Drug Discovery
Structural Biology
<p>Cryo electron microscopy plays a role in the analysis of intricate biomolecular structures by enabling researchers to outline protein shapes and connections accurately. The industry leaders in this field such, as Thermo Fisher Scientific and JEOL provide electron microscopes tailored for structural biology studies.</p>
Drug Discovery
<p>Pharmaceutical firms utilize Cryogenic Electron Microscopy (Cryo‐EM) to develop treatments by observing the interactions between drugs and receptors at a molecular level Companies such, as Gatan and Hitachi offer sophisticated Cryogenics EM solutions customized for drug exploration purposes</p>
Materials Science
<p>Cryo electron microscopy (Cryo‐EM) aids in examining materials at the nanoscale level and allows scientists to investigate the atomic structures of materials in the field of material science; Companies like Zeiss and Thermo Fisher provide customized options, for material uses.</p>
Recent Developments
August 2024
<p>Thermo Fisher Scientific unveiled a Cryogenic Electron Microscopy (CryoEM) system that incorporates artificial intelligence to speed up the processing of images.</p>
May 2024
<p>JEOL introduced a Cryogenic Electron Microscopy system designed for use, in educational and research settings.</p>
March 2024
<p>Gatan has enhanced its Cryo‐EM detector technology to achieve resolution, in the field of structural biology.</p>
Advancements in Cryogenic Electron Microscopy (Cryo‐EM) emphasize the benefits of automation and cost effectiveness well as the use of artificial intelligence for analysis. These factors contribute to the expansion of Cry0‐EM applications, in research and various industries.
Impact of Industry Transitions on the Cryo EM Market
As a core segment of the Life Science Technology industry,
the Cryo EM market develops in line with broader industry shifts.
Over recent years, transitions such as Transition to Cost-Effective Cryo-EM Solutions and Increased Automation and AI Integration have redefined priorities
across the Life Science Technology sector,
influencing how the Cryo EM market evolves in terms of demand, applications and competitive dynamics.
These transitions highlight the structural changes shaping long-term growth opportunities.
01
Transition to Cost-Effective Cryo-EM Solutions
The advancement of more affordable Cryogenic Electron Microscopy systems allows for a wider range of accessibility.
02
Increased Automation and AI Integration
The use of automation and AI technology in Cryo‑EM simplifies data processing. Improves its usefulness, in high volume laboratories.