The growing interest in natural healthcare products in North America is a key factor fueling the comfrey salve markets growth in this region with a large number of people opting for alternatives to chemically produced items and supporting companies that provide products such as comfrey salve. The urban region's of the United States and Canada particularly have a presence of people who prefer natural healthcare solutions which has led to a notable increase in market size, in these regions. In this industry landscape marked by competition​​​​​ leading companies prioritize enhancing product quality fostering innovation and establishing robust distribution networks to set their offerings apart and maintain a competitive edge. The local production of comfrey plays a role, in shaping market dynamics by enabling cost effective manufacturing and competitive pricing strategies.

In Europe's market scenario for comfrey ointment closely resembles North America's market. Differs in certain aspects because of cultural and regulatory variations between the regions. In the European Union marketplace for products undergoes rigorous testing for safety regulations that sets it apart from other regions. European customers are showing a preference, towards made or EU sourced comfrey ointments owing to their increased environmental awareness and efforts to lower carbon emissions. The situation leads to chances for domestic participants and boosts rivalry notably in nations such as Germany, France and the United Kingdom. Market stimulants in Europe encompass interest, in the beauty sector, where comfrey balm is extensively employed for its skin revitalizing attributes.