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Buccal Drug Delivery Systems Market
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Buccal Drug Delivery Systems Market

Author: Debadatta Patel - Senior Consultant, Report ID - DS1806014, Published - December 2024

Segmented in Product Type (Solid Buccal Drug Delivery Systems, Liquid Buccal Drug Delivery Systems), Application (Analgesics, Antibiotics, Antifungal Agents, Antihypertensive Agents), End-User, Technology and Regions - Global Industry Analysis, Size, Share, Trends, and Forecast 2024 – 2034

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Global Buccal Drug Delivery Systems
Market Outlook

The new Buccal Drug Delivery Systems are changing how medicines are delivered in the world by making drugs more available to the body and decreasing how often they need to be taken. The market, for Buccal drug delivery systems was estimated at $5.1 billion in 2024. It is anticipated to increase to $7.3 billion by 2030 with projections indicating a growth to around $9.9 billion by 2035. This expansion represents a compound annual growth rate (CAGR) of 6.2% over the forecast period. Offering a clever fix to common problems, in drug delivery methods of the past. These groundbreaking systems are ushering in a time where medicine can be given easily and effectively without procedures. Showing promise in transforming healthcare by administering drugs through the mouths inner lining instead of going through the digestive system and helping patients stick to their treatment plans better.


Using a Buccal Drug Delivery System relies heavily on the principles of mucosal pharmaceutics as it delivers medication directly to the bloodstream through the cheek lining for quick bioavailability of the drug without delay in effect onset timeframes. These systems are flexible. Can cater to various needs by providing options, for both overall body and localized drug administration purposes.


Market Size Forecast & Key Insights

2019
$5.1B2024
2029
$9.3B2034

Absolute Growth Opportunity = $4.2B

The Buccal Drug Delivery Systems market is projected to grow from $5.1 billion in 2024 to $9.3 billion in 2034. This represents a CAGR of 6.2%, reflecting rising demand across Pain Management Therapy, Hormonal Therapy and Treatment of Local Oral Conditions.

The Buccal Drug Delivery Systems market is set to add $4.2 billion between 2024 and 2034, with manufacturer targeting Antibiotics & Antifungal Agents Application projected to gain a larger market share.

With Increasing demand for non-invasive drug delivery methods, and Innovation in biotechnology and nanotechnology, Buccal Drug Delivery Systems market to expand 82% between 2024 and 2034.

Opportunities in the Buccal Drug Delivery Systems Market

Growing Interest in Personalized Medicine

Tailored medicine aims to create treatments that are uniquely tailored to an individuals characteristics.

Expanding Pediatric and Geriatric Applications and Innovation in Buccal Films and Tablets

In the few years there has been a rise in the request for gentle drug delivery methods that do not involve invasive procedures or pain especially, among children and the elderly. Buccal drug delivery systems offer an approach compared to injections and pills which can be challenging to give to these specific groups. This presents a chance for the pharmaceutical sector to create appealing buccal formulations that are simple to administer and designed specifically for kids and older adults.

For quite some time now buccal films and tablets have been in existence. There is a new trend that is emerging where there is a focus on creating more advanced and unique formulations. These innovations aim to improve the stability of drugs enhance compliance and boost the effectiveness of the product. With the increasing emphasis on patients in healthcare practices these groundbreaking products could open up opportunities, in the market.

Growth Opportunities in North America and Europe

Europe Outlook

Europe holds the second-largest share in the Buccal Drug Delivery Systems market. The presence of robust healthcare systems, especially in countries like Germany, France, and the UK, drive market growth. Europe also boasts high technological advancements and substantial investment in medical research, fostering the development and acceptance of buccal drug delivery systems.

North America Outlook

North America leads the Buccal Drug Delivery Systems market due to its healthcare infrastructure and government backing for research and development efforts as well as a well informed patient population. The region hosts top pharmaceutical and biomedical firms that play a vital role in its substantial market dominance. Intense competition, among industry players motivates the constant unveiling of cutting edge and effective buccal drug delivery systems. In addition the region offers a variety of opportunities as the number of diseases that demand effective drug delivery methods continues to increase.

North America Outlook

North America leads the Buccal Drug Delivery Systems market due to its healthcare infrastructure and government backing for research and development efforts as well as a well informed patient population. The region hosts top pharmaceutical and biomedical firms that play a vital role in its substantial market dominance. Intense competition, among industry players motivates the constant unveiling of cutting edge and effective buccal drug delivery systems. In addition the region offers a variety of opportunities as the number of diseases that demand effective drug delivery methods continues to increase.

Europe Outlook

Europe holds the second-largest share in the Buccal Drug Delivery Systems market. The presence of robust healthcare systems, especially in countries like Germany, France, and the UK, drive market growth. Europe also boasts high technological advancements and substantial investment in medical research, fostering the development and acceptance of buccal drug delivery systems.

Growth Opportunities in North America and Europe

Established and Emerging Market's Growth Trend 2025–2034

1

Major Markets : United States, Germany, China, Japan, United Kingdom are expected to grow at 4.0% to 6.0% CAGR

2

Emerging Markets : Brazil, India, South Africa are expected to grow at 7.1% to 8.6% CAGR

Market Analysis Chart

Oral drug delivery systems provide improved drug stability by avoiding the metabolism in the liver that can degrade drug compounds and make them less effective. This increased stability is a factor driving pharmaceutical companies to embrace these delivery methods. Furthermore the ease of use and patient friendly nature of drug delivery systems make them a favorable choice, for both patients and healthcare providers.

Recent Developments and Technological Advancement

March 2024

Pharmavite LLC unveiled two buccal drug delivery systems aimed at improving the absorption of vitamins and supplements.

June 2024

Nemaura Pharma has unveiled a cutting edge drug delivery system called Micro Patch that is said to enhance the release of drugs into the bloodstream more effectively.

August 2024

Novartis Pharmaceuticals achieved a milestone in the field of buccal drug delivery systems by successfully concluding the phase III trials for their groundbreaking opioid analgesic buccal system.

In times the Buccal Drug Delivery Systems market has experienced notable growth due to progressions in biotechnology and pharmaceutical industries. The market is distinguished by the creation of new products and techniques to enhance drug delivery and absorption. An important trend influencing this growing market is the demand for user solutions that prioritize patient comfort. Consumers are showing a preference, for invasive and simple delivery methods that contribute to improved health results.

Impact of Industry Transitions on the Buccal Drug Delivery Systems Market

As a core segment of the Other Healthcare industry, the Buccal Drug Delivery Systems market develops in line with broader industry shifts. Over recent years, transitions such as Innovation in Bio-Adhesive Materials and Digitization and Personalized Medicine have redefined priorities across the Other Healthcare sector, influencing how the Buccal Drug Delivery Systems market evolves in terms of demand, applications and competitive dynamics. These transitions highlight the structural changes shaping long-term growth opportunities.

1

Innovation in Bio-Adhesive Materials:

The Buccal Drug Delivery Systems market has seen a shift towards using advanced bio adhesive materials that improve the stickiness of buccal drugs in the mouth cavity for longer durations to enhance drug effectiveness significantly It represents a revolutionary advancement that enhances treatment results and opens up fresh prospects, for pharmaceutical firms entering this sector

2

Digitization and Personalized Medicine:

A significant shift is occurring with the merging of digitization and customization, in pharmaceutical delivery methods. The emergence of healthcare technologies has ushered in a fresh era of tailored medical treatments that aim to enhance dosage precision according to the unique requirements of each patients health condition.

Global Events Shaping Future Growth

The chart below highlights how external events including emerging market developments, regulatory changes, and technological disruptions, have added another layer of complexity to the Other Healthcare industry. These events have disrupted supply networks, changed consumption behavior, and reshaped growth patterns. Together with structural industry transitions, they demonstrate how changes within the Other Healthcare industry cascade into the Buccal Drug Delivery Systems market, setting the stage for its future growth trajectory.

Market Dynamics and Supply Chain

Driver: Increasing Demand for Non-Invasive Drug Delivery Methods, and Growing Prevalence of Chronic Diseases

The healthcare sector worldwide is also moving towards invasive treatment methods with a rising interest in Buccal Drug Delivery Systems lately. This innovative approach involves delivering substances through the buccal mucosa without any invasion; its becoming popular due, to its effectiveness and patient friendly nature. Pharmaceutical companies are also increasingly embracing this technology for its ease of use and patient satisfaction.
With rising cases of chronic conditions like diabetes, cardiovascular diseases, cancer, etc., the need for effective and efficient drug delivery systems increases.
Progress in biotechnology and nanotechnology is also having an influence on the Buccal Drug Delivery Systems industry. Innovations in these fields enable the creation of delivery systems thatre more compact, efficient and reliable. Ongoing research and development in this area ensures bioavailability and drug absorption reduced first pass metabolism and improved patient adherence. These encouraging aspects lead to a growing demand, for the market.

Restraint: Regulation Roadblocks

The expansion of Buccal Drug Delivery Systems in the market may face obstacles due to government rules and legal structures in place. These systems must undergo testing and approval procedures that demand significant investments of money and time—posing a notable challenge to the market. Furthermore the absence of harmonized standards for these innovative delivery systems, among various nations can add complexity to securing essential approvals and permits ultimately impeding the pace at which these systems can enter the commercial sphere.

Challenge: Limited Drug Suitability

One important limitation is the restricted selection of medications that can be used for delivering drugs through the inner lining of the cheek (buccal drug delivery).

Supply Chain Landscape

Raw Material Suppliers

BASF SE

Evonik Industries AG

API Development

Teva Pharmaceutical Industries Ltd.

Mylan N.V

Buccal Drug Formulation Manufacturers
Macleods Pharmaceuticals / Sun Pharmaceutical Industries Ltd
Distribution and End-User Industry
CVS Health / Walgreens Boot Alliance
Raw Material Suppliers

BASF SE

Evonik Industries AG

API Development

Teva Pharmaceutical Industries Ltd.

Mylan N.V

Buccal Drug Formulation Manufacturers

Macleods Pharmaceuticals

Sun Pharmaceutical Industries Ltd

Distribution and End-User Industry

CVS Health

Walgreens Boot Alliance

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Leading Providers and Their Strategies

Application AreaIndustryLeading ProvidersProvider Strategies
Chronic Pain Management
Pharmaceuticals
Novartis, Johnson & Johnson
Development of controlled-release dosage forms, investing heavily in research and development to increase patient compliance
Diabetes Management
Healthcare
Eli Lilly, Novo Nordisk
Innovation of painless insulin delivery systems, focusing on patient comfort while maintaining drug efficacy
Cardiovascular Diseases
Pharmaceuticals
Pfizer, AstraZeneca
Design of transmucosal patches to ensure consistent drug levels, research on personalized medicine methodologies
Smoking Cessation Programs
Healthcare
GlaxoSmithKline, Novartis
Development of nicotine replacement products, introduction of user-friendly drug delivery systems improving adherence to treatment

Elevate your strategic vision with in-depth analysis of key applications, leading market players, and their strategies. The report analyzes industry leaders' views and statements on the Buccal Drug Delivery Systems market's present and future growth.

Our research is created following strict editorial standards. See our Editorial Policy

Applications of Buccal Drug Delivery Systems in Hormonal Therapy, Pain Management Therapy and Treatment of Local Oral Conditions

Hormonal Therapy

Many medical professionals use this system for hormone treatments like testosterone replacement therapy well. It ensures regulated administration of medication which helps patients stick to their treatment plans. Known companies in the market such as Novartis demonstrate the effectiveness of this system with products, like the Testosterone Buccal System.

Pain Management Therapy

In pain management for individuals with ailments such as cancer Buccal Drug Delivery Systems play a significant role by offering quick relief and enhanced bioavailability through direct absorption into the bloodstream without going through initial metabolism Companies like Teva Pharmaceuticals have led the way, in this area with their development of buccal tablets containing Fentanyl

Treatment of Local Oral Conditions

Oral drug delivery in the region is commonly employed to address localized oral issues such as oral ulcers and fungal infections among others Yes! Its beneficial to focus treatment in an area as it helps minimize the overall exposure of drugs in the body thereby decreasing the likelihood of side effects Takedae Pharmaceuticals and other companies are leading the way, in utilizing this innovative approach

Buccal Drug Delivery Systems vs. Substitutes:
Performance and Positioning Analysis

Offered by drug delivery systems is a non invasive and convenient dosing option as an alternative to injections. Contrary to intake methods these systems bypass the gastrointestinal tract result in higher bioavailability. Given the increasing focus on patient centered therapies, the potential for market expansion, for this system is evident.

Buccal Drug Delivery Systems
  • Oral Drug Delivery Systems /
  • Transdermal Drug Delivery Systems
    Easy administration, Rapid drug absorption and onset of action
    Potential for local irritation, Variable absorption due to saliva flow
    Rapid drug absorption, Patient compliance
    Risk of gastrointestinal damage, Potential for lower bioavailability

Buccal Drug Delivery Systems vs. Substitutes:
Performance and Positioning Analysis

Buccal Drug Delivery Systems

  • Easy administration, Rapid drug absorption and onset of action
  • Potential for local irritation, Variable absorption due to saliva flow

Oral Drug Delivery Systems / Transdermal Drug Delivery Systems / Intranasal Drug Delivery Systems

  • Rapid drug absorption, Patient compliance
  • Risk of gastrointestinal damage, Potential for lower bioavailability

Offered by drug delivery systems is a non invasive and convenient dosing option as an alternative to injections. Contrary to intake methods these systems bypass the gastrointestinal tract result in higher bioavailability. Given the increasing focus on patient centered therapies, the potential for market expansion, for this system is evident.

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Research Methodology

This market research methodology defines the Buccal Drug Delivery Systems market scope, gathers reliable data, and validates findings using integrated primary and secondary research. Our systematic framework ensures precise market sizing, growth trend analysis, and competitive benchmarking.


Secondary Research Approach


We begin secondary research by defining the targeted market at Country and Regional levels. As part of the Other Healthcare ecosystem, we analyze Buccal Drug Delivery Systems across Pharmaceutical Companies, Research Laboratories, and Healthcare Institutions Applications. Our team gathers data systematically from country level ministerial sources, industry associations & federations, trade databases, company annual & quarterly reports and other credential sources, enabling us to map global and regional market size, pricing trends, regulatory standards, and technology advancements.


Key Sources Referenced:


We benchmark competitors such as Johnson & Johnson Services Inc, Novartis AG, and Takeda Pharmaceutical Company Limited by reviewing company financial statements, and regulatory filings. Our secondary insights identify key market drivers and constraints, forming the analytical foundation for primary research.


Primary Research Methods


We conduct structured interviews and surveys with industry stakeholders, including Raw Material Suppliers, API Development, and Buccal Drug Formulation Manufacturers. Our geographic coverage spans Americas (40%), Europe (30%), Asia-Pacific (25%) and Middle East & Africa (5%). Our online surveys generally achieve a response rate of above 65%, and telephone interviews yield 60%, resulting in above 92% confidence level with a ±7% margin of error.


Through targeted questionnaires and in-depth interviews, we capture purchase intent, adoption barriers, brand perception across Segment Type. We use interview guides to ensure consistency and anonymous survey options to mitigate response bias. These primary insights validate secondary findings and align market sizing with real-world conditions.


Market Engineering & Data Analysis Framework


Our data analysis framework integrates Top-Down, Bottom-Up, and Company Market Share approaches to estimate and project market size with precision.


Top-down & Bottom-Up Process


In Top-down approach, we disaggregate global Other Healthcare revenues to estimate the Buccal Drug Delivery Systems segment, using historical growth patterns to set baseline trends. Simultaneously, in Bottom-up approach, we aggregate Country-Level Demand Data to derive regional and global forecasts, which provide granular consumption insights. By reconciling both approaches, we ensure statistical precision and cross-validation accuracy.


We evaluate the supply chain, spanning Raw Material Suppliers (BASF SE, Evonik Industries AG), API Development (Teva Pharmaceutical Industries Ltd., Mylan N.V), and Buccal Drug Formulation Manufacturers. Our parallel substitute analysis examines Oral Drug Delivery Systems, Transdermal Drug Delivery Systems, and Intranasal Drug Delivery Systems, highlighting diversification opportunities and competitive risks.


Company Market Share & Benchmarking


We benchmark leading companies such as Johnson & Johnson Services Inc, Novartis AG, and Takeda Pharmaceutical Company Limited, analyzing their capabilities in pricing, product features, technology adoption, and distribution reach. By assessing company-level revenues and product portfolios, we derive market share comparisons, clarifying competitive positioning and growth trajectories across the ecosystem.


Our integration of data triangulation, supply chain evaluation, and company benchmarking, supported by our proprietary Directional Superposition methodology enables us to deliver precise forecasts and actionable strategic insights into the Buccal Drug Delivery Systems market.


Quality Assurance and Compliance


We cross-reference secondary data with primary inputs and external expert reviews to confirm consistency. Further, we use stratified sampling, anonymous surveys, third-party interviews, and time-based sampling to reduce bias and strengthen our results.


Our methodology is developed in alignment with ISO 20252 standards and ICC/ESOMAR guidelines for research ethics. The study methodology follows globally recognized frameworks such as ISO 20252 and ICC codes of practice.

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Buccal Drug Delivery Systems Market Data: Size, Segmentation & Growth Forecast

Report AttributeDetails
Market Value in 2025USD 5.4 billion
Revenue Forecast in 2034USD 9.3 billion
Growth RateCAGR of 6.2% from 2025 to 2034
Base Year for Estimation2024
Industry Revenue 20245.1 billion
Growth OpportunityUSD 4.2 billion
Historical Data2019 - 2023
Growth Projection / Forecast Period2025 - 2034
Market Size UnitsMarket Revenue in USD billion and Industry Statistics
Market Size 20245.1 billion USD
Market Size 20276.1 billion USD
Market Size 20296.9 billion USD
Market Size 20307.3 billion USD
Market Size 20349.3 billion USD
Market Size 20359.9 billion USD
Report CoverageMarket revenue for past 5 years and forecast for future 10 years, Competitive Analysis & Company Market Share, Strategic Insights & trends
Segments CoveredProduct Type, Application, End-User, Technology
Regional scopeNorth America, Europe, Asia Pacific, Latin America and Middle East & Africa
Country scopeU.S., Canada, Mexico, UK, Germany, France, Italy, Spain, China, India, Japan, South Korea, Brazil, Mexico, Argentina, Saudi Arabia, UAE and South Africa
Companies ProfiledJohnson & Johnson Services Inc, Novartis AG, Takeda Pharmaceutical Company Limited, Pfizer Inc, Roche Holding AG, Bausch Health Companies Inc, Merck Sharp & Dohme Corp, Allergan plc, Alembic Pharmaceuticals Limited, Sanofi, Teva Pharmaceutical Industries Ltd and Bayer AG
CustomizationFree customization at segment, region or country scope and direct contact with report analyst team for 10 to 20 working hours for any additional niche requirement which is almost equivalent to 10% of report value

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Table of Contents

Industry Insights Report - Table Of Contents

Chapter 1

Executive Summary

Major Markets & Their Performance - Statistical Snapshots

Chapter 2

Research Methodology

2.1Axioms & Postulates
2.2Market Introduction & Research MethodologyEstimation & Forecast Parameters / Major Databases & Sources
Chapter 3

Market Dynamics

3.1Market OverviewDrivers / Restraints / Opportunities / M4 Factors
3.2Market Trends
3.2.1Introduction & Narratives
3.2.2Market Trends - Impact Analysis(Short, Medium & Long Term Impacts)
3.3Supply Chain Analysis
3.4Porter's Five ForcesSuppliers & Buyers' Bargaining Power, Threat of Substitution & New Market Entrants, Competitive Rivalry
Chapter 4

Buccal Drug Delivery Systems Market Size, Opportunities & Strategic Insights, by Product Type

4.1Solid Buccal Drug Delivery Systems
4.2Liquid Buccal Drug Delivery Systems
Chapter 5

Buccal Drug Delivery Systems Market Size, Opportunities & Strategic Insights, by Application

5.1Analgesics
5.2Antibiotics
5.3Antifungal Agents
5.4Antihypertensive Agents
Chapter 6

Buccal Drug Delivery Systems Market Size, Opportunities & Strategic Insights, by End-User

6.1Pharmaceutical Companies
6.2Research Laboratories
6.3Healthcare Institutions
Chapter 7

Buccal Drug Delivery Systems Market Size, Opportunities & Strategic Insights, by Technology

7.1Matrix System
7.2Reservoir System
7.3Adhesive Diffusion System
7.4Multi-layered System
Chapter 8

Buccal Drug Delivery Systems Market, by Region

8.1North America Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.1.1U.S.
8.1.2Canada
8.2Europe Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.2.1Germany
8.2.2France
8.2.3UK
8.2.4Italy
8.2.5The Netherlands
8.2.6Rest of EU
8.3Asia Pacific Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.3.1China
8.3.2Japan
8.3.3South Korea
8.3.4India
8.3.5Australia
8.3.6Thailand
8.3.7Rest of APAC
8.4Middle East & Africa Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.4.1Saudi Arabia
8.4.2United Arab Emirates
8.4.3South Africa
8.4.4Rest of MEA
8.5Latin America Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.5.1Brazil
8.5.2Mexico
8.5.3Rest of LA
8.6CIS Buccal Drug Delivery Systems Market Size, Opportunities, Key Trends & Strategic Insights
8.6.1Russia
8.6.2Rest of CIS
Chapter 9

Competitive Landscape

9.1Competitive Dashboard & Market Share Analysis
9.2Company Profiles (Overview, Financials, Developments, SWOT)
9.2.1Johnson & Johnson Services Inc
9.2.2Novartis AG
9.2.3Takeda Pharmaceutical Company Limited
9.2.4Pfizer Inc
9.2.5Roche Holding AG
9.2.6Bausch Health Companies Inc
9.2.7Merck Sharp & Dohme Corp
9.2.8Allergan plc
9.2.9Alembic Pharmaceuticals Limited
9.2.10Sanofi
9.2.11Teva Pharmaceutical Industries Ltd
9.2.12Bayer AG