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Vitamin K2 Market

The market for Vitamin K2 was estimated at $174 million in 2025; it is anticipated to increase to $332 million by 2030, with projections indicating growth to around $633 million by 2035.

Report ID:DS1805006
Author:Debadatta Patel - Senior Consultant
Published Date:
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Life Science
Nutraceuticals
Vitamin K2
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Report Summary
Market Data
Methodology
Table of Contents

Global Vitamin K2 Market Outlook

Revenue, 2025

$174M

Forecast, 2035

$633M

CAGR, 2026 - 2035

13.8%

The Vitamin K2 industry revenue is expected to be around $173.8 million in 2026 and expected to showcase growth with 13.8% CAGR between 2026 and 2035. The Vitamin K2 market shows strong potential because it has become a vital component for worldwide nutraceutical and pharmaceutical businesses because people now prioritize preventive healthcare and the market has grown due to aging populations and scientific evidence supporting its benefits for bone health and heart wellness. The MK 7 segment has established itself as the performance standard in the competitive market because it generates the highest industry revenues through its $132.8 million sales in 2025. The product achieves its market success because it provides better bioavailability and longer half life and works well as a single daily vitamin K2 supplement. The market continues to support Vitamin K2 product development through capsule and gummy and functional food innovations while regulatory bodies focus on osteoporosis prevention and heart health which strengthens its position for manufacturers who want scientific evidence to differentiate their brands.

The family contains fat soluble Vitamin K2, also known as Menaquinone,, also known as Menaquinone (MK), which activates essential proteins including osteocalcin and matrix gamma-carboxyglutamic acid protein to control calcium metabolism by steering bone calcium deposition while preventing blood vessel calcification. The total Vitamin K2 market demand reaches 64.8% because bone health and heart health applications work together to support dietary supplement and fortified food and specific joint integrity and vascular protection formulations. The market shows two main trends which involve using fermented MK-7 from natural sources and developing delivery systems that are both clean label and vegan and combining Vitamin K2 with vitamin D3 and calcium and magnesium at higher potency levels. The market uses premium pricing for evidence based solutions because consumers want them and scientists have proven their effectiveness through research. The market dynamics establish Vitamin K2 as a fundamental ingredient which serves as a base for supplements and functional foods and medical nutrition products which support extended skeletal and cardiovascular health.

Vitamin K2 market outlook with forecast trends, drivers, opportunities, supply chain, and competition 2025-2035
Vitamin K2 Market Outlook

Market Key Insights

  • The Vitamin K2 market is projected to grow from $173.8 million in 2025 to $633 million in 2035. This represents a CAGR of 13.8%, reflecting rising demand across Bone Health, Heart Health, and Blood Clotting.

  • The market leaders Gnosis by Lesaffre, Kappa Bioscience AS and J Oil Mills Inc. determine the competitive dynamics of this industry.

  • The Vitamin K2 market depends on the United States and France as its leading customer bases which will experience growth at 12.4% to 16.6% CAGR from 2025 to 2030.

  • The research predicts that India and South Korea and Spain will experience the most significant market expansion at rates between 9.7% and 14.5% CAGR.

  • The Vitamin K2 market will experience $42 million additional growth because of Transition like Growing Consumer Awareness during the period from 2030 to 2030.

  • The Vitamin K2 market will experience a $459 million growth span from 2025 to 2035 while Heart Health & Blood Clotting Application from manufacturers will control an expanding market segment.

  • The Vitamin K2 market will experience a 264% growth from 2025 to 2035 because people understand its health advantages and new extraction technologies have emerged.

vitamin k2 market size with pie charts of major and emerging country share, CAGR, trends for 2025 and 2032
Vitamin K2 - Country Share Analysis

Opportunities in the Vitamin K2

The rise of digitally native consumers who buy Vitamin K2 directly from ecommerce platforms has also established a new market segment which lacks products in sports nutrition and prenatal vitamins. The market shows preference for flexible MK 7 because it enables daily administration yet MK 4 continues to expand its market share for specialty products which require quick results. The combination of targeted online subscriptions with influencer led education and strategic alliances between telehealth services and online pharmacies will drive the fastest growth for MK 7 based performance and maternal and post partum recovery products.

Growth Opportunities in North America and Asia Pacific

North American consumers primarily use Vitamin K2 for bone health and cardiovascular health purposes through premium nutraceuticals which focus on healthy aging and post menopausal wellness. The market offers three main business opportunities which include menaquinone-7 formulations with distinct properties and solid scientific backing and delivery systems that use natural ingredients and plant based materials and combination products which support bone and heart health in dietary supplements and functional foods. The market competition between regional contract manufacturers and private label brands and specialty ingredient suppliers who focus on pharmaceutical grade quality and tight regulatory compliance has increased which leads to new developments in stability and bioavailability and evidence based claim support. The market has three main regional factors which drive its growth because osteoporosis and arterial calcification affect many people in this region and customers can easily access specialty nutrition products through advanced retail and e commerce channels and healthcare providers now use Vitamin K2 protocols as part of their preventive care approaches.
The Asia Pacific region bases its Vitamin K2 market demand on two main applications which include bone health support and blood clotting assistance while heart health applications gain importance because people understand better how to prevent cardiovascular diseases in their aging and urbanizing society. The market offers three main business opportunities which include fortified functional foods and traditional dietary supplements and Vitamin K2 supplements that match specific regional eating habits and budget ranges and natural ingredient preferences. The market competition exists because of powerful local and regional brands which include ingredient manufacturers and OEM/ODM supplement producers who use adaptable dosing systems and local regulatory standards to enter new markets quickly. The main factors which drive market growth stem from two main elements: the fast paced population aging process and people gaining more money to spend and public institutions dedicating resources to prevent fractures and improve mobility and customers learning about Vitamin K2s specific health benefits for bones and blood vessels.

Market Dynamics and Supply Chain

01

Driver: Growing Awareness of Bone Health Importance and Rising Preventive Wellness Adoption Worldwide

Increasing consumer awareness of bone health and preventive wellness is also a key driver for the vitamin K2 market. Aging populations in developed and emerging regions are also more focused on maintaining bone strength and reducing osteoporosis risk, driving demand for functional nutrients that support skeletal health. Vitamin K2, particularly the MK‑7 form, has also gained traction among health‑conscious adults seeking alternatives to traditional calcium‑only supplements, as it helps activate osteocalcin for effective calcium utilization. At the same time, broader wellness trends are also elevating preventive health spending, with many consumers proactively adopting nutrient‑rich supplements to reduce future health burdens. This shift toward preventive care has also been amplified by digital health information, social media, and health influencers emphasizing lifestyle interventions that include targeted micronutrients like vitamin K2. Supplement brands and nutraceutical ingredient suppliers are also responding with educational campaigns, clinical studies on MK‑7 efficacy, and product innovations that align with preventive health goals, bolstering the vitamin K2 market across demographic segments.
A significant standalone driver for the vitamin K2 market is also the expansion of clinical research demonstrating its role in cardiovascular health. Emerging studies suggest that vitamin K2 helps regulate calcium deposition in arteries, supporting arterial flexibility and cardiovascular health, which resonates with consumers seeking heart health solutions beyond traditional omega‑3s and antioxidants. This scientific backing has also encouraged healthcare professionals to recommend vitamin K2 for arterial support, elevating market credibility. Nutraceutical companies and ingredient brands are also increasingly investing in research partnerships and publishing data to differentiate MK‑7 formulations with proven heart health benefits, further stimulating demand among middle‑aged and older adults focused on holistic cardiovascular wellness.
02

Restraint: Limited Consumer Awareness and Misunderstanding of Vitamin K2 Benefits Constrain Market Adoption

Despite growing interest in wellness supplements, many consumers remain unaware of vitamin K2’s distinct advantages compared to vitamin K1, especially for bone and cardiovascular health. This lack of understanding can depress demand, particularly among mainstream supplement buyers who default to calcium or multivitamins without K2. For example, limited educational marketing has slowed uptake in emerging markets, reducing revenue potential for brands and leaving vitamin K2 underrepresented in preventive health regimens.
03

Opportunity: Emerging cardiovascular-focused functional foods with Vitamin K2 fortification across European and Asia-Pacific premium wellness brands and Accelerating adoption of Vitamin K2 bone-health supplements among aging women and seniors in North America

The European and Asian Pacific regions have their innovation focus on cardiovascular health through Vitamin K2 enriched functional food products which include premium dairy products and plant based beverages and heart health shots. The market for highly bioavailable MK 7 will grow faster than MK 4 because it shows better global revenue potential with a 14.5% annual growth rate. The market offers two unexplored business potential which includes cholesterol management through clean label Vitamin K2 fortification for middle aged consumers who watch their cholesterol levels and co branded product releases with well known food companies that use Vitamin K2 as a unique ingredient in their preventive cardiometabolic product lines.
The aging population of North America looks for Vitamin K2 to support their bone health but this supplement has not only spread into mainstream markets beyond specialized dietary supplement channels. The MK 7 segment will achieve market leadership through its clinical evidence because global sales projections show 132.80 million in 2025 will expand to 261.35 million by 2030 at 14.5% annual growth rate. The market for womens health nutraceuticals and calcium combinations and pharmacist led personalized protocols offers brands an opportunity to serve unmet customer needs through MK 7 integration. MK 4 maintains its position as a specialized therapeutic prescription product which remains limited in its market presence.
04

Challenge: Regulatory Variability and Labeling Restrictions Hinder Global Market Growth and Claims

Differing regulatory frameworks across regions impose challenges for vitamin K2 manufacturers and marketers. Strict claims regulations in markets like the EU and parts of Asia limit health benefit statements on packaging and advertising, forcing companies to invest heavily in clinical substantiation or avoid certain markets. These constraints increase compliance costs and slow entry into new geographies, dampening revenue growth and slowing adoption by consumers who rely on clear, evidence‑based product messaging.

Supply Chain Landscape

1

Precursor Production

Novozymes A/SBASF SE
2

Vitamin K2 Fermentation

Gnosis by LesaffreKappa Bioscience ASJ-Oil Mills Inc
3

Vitamin K2 Formulation

BASF SEGnosis by LesaffreKappa Bioscience AS
4

End-use Applications

Vitamin K2 dietary supplementsFunctional foodsPharmaceutical nutraceuticals
Vitamin K2 - Supply Chain

Use Cases of Vitamin K2 in Bone Health & Blood Clotting

Bone Health : Vitamin K2 plays a vital role in bone health by activating osteocalcin, a protein essential for binding calcium to the bone matrix, thus contributing to increased bone mineral density and reduced fracture risk. The MK‑7 form of vitamin K2 is most widely used in bone health supplements due to its superior bioavailability and longer half‑life compared to MK‑4. Consumers, especially older adults and postmenopausal women, choose MK‑7 to support skeletal strength. Leading nutraceutical companies such as NattoPharma, DSM, and Kyowa Hakko leverage clinically studied MK‑7 ingredients to differentiate their products, emphasize evidence‑based benefits, and maintain strong market positions in bone support formulations.
Heart Health : In heart health applications, vitamin K2 supports cardiovascular function by regulating calcium deposition and directing calcium away from arterial walls toward bones, thereby helping maintain arterial flexibility. Here again, vitamin K2 as MK‑7 is preferred due to its sustained circulation levels and enhanced systemic effect. This makes it attractive in heart health and arterial support supplements for adults seeking to promote healthy blood vessel function. Key market players like BASF, Gnosis by Lesaffre, and Kappa Bioscience supply high‑purity MK‑7 to global supplement brands, highlighting cardiovascular wellness claims and capitalizing on rising consumer awareness of nontraditional heart health nutrients.
Blood Clotting : Vitamin K2 contributes to blood clotting by facilitating the activation of clotting factors produced in the liver, helping the body respond appropriately to injury. While vitamin K1 historically dominated this application, emerging research supports K2’s complementary role in optimizing coagulation pathways. Athletes and individuals with specific vitamin K needs may include K2 in combination formulas to support balanced hemostasis. Nutraceutical suppliers such as Natco Pharma, Lonza, and Prinova Group offer vitamin K2 blends targeting blood clotting and overall wellness, combining quality assurance with strong regulatory compliance in dietary supplement markets.

Recent Developments

Recent developments in the Menaquinone market reflect rising demand for MK‑7 supplements, expanded vegan and plant‑based formulations, and increased emphasis on bone and cardiovascular health benefits. Manufacturers are launching high‑purity, fermentation‑derived K2 ingredients to meet clean‑label and sustainability preferences among consumers. A key market trend is the integration of K2 with multinutrient formulas alongside vitamin D3 and calcium, enhancing nutraceutical efficacy and broadening functional supplement portfolios in global wellness markets.

March 2024 : SunWay Biotech teamed with Gnosis by Lesaffre to debut MenaQ7 Metabolic, a blend of vitamin K2 as MK‑7 and statin‑free red yeast rice fermentate to support heart and bone health.
July 2024 : At Vitafoods Europe, Kappa Bioscience showcased seven new K2VITAL white‑label vitamin K2 products, expanding dosage formats and delivery concepts for global nutraceutical brands.
September 2024 : Gnosis by Lesaffre presented MenaQ7 vitamin K2 at the Denk Ingredient Symposium in Munich, emphasizing its role in women’s health and broader functional nutrition applications.

Impact of Industry Transitions on the Vitamin K2 Market

As a core segment of the Nutraceuticals industry, the Vitamin K2 market develops in line with broader industry shifts. Over recent years, transitions such as Growing Consumer Awareness and Shift towards Vegan and Natural Supplements have redefined priorities across the Nutraceuticals sector, influencing how the Vitamin K2 market evolves in terms of demand, applications and competitive dynamics. These transitions highlight the structural changes shaping long-term growth opportunities.
01

Growing Consumer Awareness

The global Vitamin K2 market experiences transformation because consumers now understand the particular advantages of Vitamin K2 which drives them to select dietary supplements and functional foods for bone health and cardiovascular protection. The market shows increasing interest in specific Vitamin K2 supplements because scientists have established their direct connection to three essential health benefits which include osteoporosis prevention and better arterial flexibility and extended preventive care results. The market shift toward essential nutraceuticals has created a new perception which makes these products essential for consumers. The market growth of Vitamin K2 products will reach $42 million during 2030 because consumers now view these products as essential. Manufacturers who succeed in teaching both consumers and healthcare professionals about their products will obtain most of the growing market value.
02

Shift towards Vegan and Natural Supplements

The shift towards vegan and naturally sourced supplements has significantly influenced the vitamin K2 market, as consumers increasingly prefer plant-based, non-animal-derived products for health and ethical reasons. Vitamin K2, traditionally sourced from animal tissues or fermented foods, now sees growing production from natto-derived MK‑7 and microbial fermentation methods, offering clean-label, vegan-friendly alternatives. This transition impacts nutraceutical and functional food industries, enabling supplement brands to target vegetarian and vegan consumers while expanding into fortified foods and beverages. For example, companies like NattoPharma, DSM, and Kappa Bioscience have developed high-purity, plant-based MK‑7 formulations, enhancing product appeal, meeting regulatory and sustainability trends, and driving wider adoption of vitamin K2 in bone, heart, and general wellness products.