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Trilaciclib Dihydrochloride Market
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Trilaciclib Dihydrochloride Market

Author: Debadatta Patel - Senior Consultant, Report ID - DS1802554, Published - June 2025

Segmented in Product Form (Intravenous Solution, Tablet), Applications (Chemotherapy-Induced Myelosuppression Prevention, Small Cell Lung Cancer Treatment, Metastatic Triple-Negative Breast Cancer Treatment, Others), Distribution Channel, Possible Combinations and Regions - Global Industry Analysis, Size, Share, Trends, and Forecast 2024 – 2034

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Global Trilaciclib Dihydrochloride
Market Outlook

The market, for Trilaciclib Dihydrochloride was estimated at $656.8 million in 2024; and it is anticipated to increase to $985.7 million by 2030 with projections indicating a growth to around $1.4 billion by 2035. This expansion represents a compound annual growth rate (CAGR) of 7.0% over the forecast period. This optimistic growth trend in the Trilaciclib dihydrochloride sector can be attributed to a multitude of significant factors. The primary driver of this expansion draws from its pivotal role in cancer treatment, coupled with a robust increase in the global oncology sector. The high-level efficacy of Trilaciclib dihydrochloride, substantiated through extensive clinical trials, has optimized its integration within various therapeutic regimens. Additionally, growing awareness and advancements in healthcare technologies have positively impacted the market expansion, thereby scaling its ongoing relevance in the pharmaceutical industry.


Trilaciclib dihydrochloride, a potent cyclin-dependent kinase 4/6 inhibitor, is primarily employed in oncology therapeutics. The compound has been shown to reduce instances of chemotherapy-induced myelosuppression. It, therefore, plays a crucial role in improving the quality of life for patients undergoing intense cancer treatment. While the primary application remains within the oncology realm, research is ongoing for potential roles in other health modalities as well.


Market Size Forecast & Key Insights

2019
$656M2024
2029
$1.3B2034

Absolute Growth Opportunity = $635M

The Trilaciclib Dihydrochloride market is projected to grow from $656.8 million in 2024 to $1.29 billion in 2034. This represents a CAGR of 7.0%, reflecting rising demand across Oncology Treatment and Hematopoiesis Preservation.

The Trilaciclib Dihydrochloride market is set to add $635 million between 2024 and 2034, with manufacturer targeting Small Cell Lung Cancer Treatment & Metastatic Triple-Negative Breast Cancer Treatment Applications projected to gain a larger market share.

With Increasing prevalence of cancer, and Technological advancements in drug development, Trilaciclib Dihydrochloride market to expand 97% between 2024 and 2034.

Opportunities in the Trilaciclib Dihydrochloride Market

Strategic Collaborations

Partnerships with global pharmaceutical leaders offer another chance for Trilaciclib dihydrochloride to enhance market penetration. Through strategic collaborations, the drug can potentially enter new markets, streamline distribution, and reach a broader patient demographic. Consequently, such alliances can significantly influence the global market position of Trilaciclib dihydrochloride.

Exploring New Segments and Technological Innovations

As discussed earlier, Trilaciclib dihydrochloride has proven efficacy in cancer treatment and significant success in clinical trials. However, the medication is yet to be fully exploited in carcinoma areas, including breast cancer, where current therapies show limited effectiveness. By tapping into this untapped segment, Trilaciclib dihydrochloride may experience substantial market growth.

The progressive technological advancements in the pharmaceutical industry present a promising for Trilaciclib dihydrochloride. Moreover, embracing advanced drug delivery systems may optimize its administration, improve patient experience, and thus potentially boost its market acceptance. Additionally, continuous efforts in scientific research can uncover innovative applications for Trilaciclib dihydrochloride, further driving its market expansion.

Growth Opportunities in North America and Asia-Pacific

Asia Pacific Outlook

The Asia-Pacific region is experiencing accelerated growth in the Trilaciclib dihydrochloride market. This progression is due to the regions burgeoning population, rising disposable income, and increasing healthcare investment. Nations such as China and India present immense potential, with escalating incidences of cancer and substantial growth in medical tourism. Increasing government initiatives to improve healthcare services, combined with emerging pharmaceutical manufacturers, stimulate the market further. However, patent infringement issues and imitation drugs create significant competition and act as potential roadblocks. The regions growth is also driven by its growing pharmaceutical exports, supplementing the global availability of Trilaciclib dihydrochloride.

North America Outlook

North America arguably powers the global demand for Trilaciclib dihydrochloride, underpinned by advanced healthcare infrastructure and a robust pharmaceutical research environment. Rapid adoption of innovative cancer therapies, driven by the high prevalence of malignancies such as small-cell lung cancer, has created an extensive market for Trilaciclib dihydrochloride. Further, top-tier pharmaceutical companies intensify the competitive landscape, continually seeking approvals for new applications of Trilaciclib dihydrochloride from the FDA, driving growth. Sponsoring clinical trials and promoting research and development activities provide additional momentum. However, stringent regulations and patent cliffs pose challenges.

North America Outlook

North America arguably powers the global demand for Trilaciclib dihydrochloride, underpinned by advanced healthcare infrastructure and a robust pharmaceutical research environment. Rapid adoption of innovative cancer therapies, driven by the high prevalence of malignancies such as small-cell lung cancer, has created an extensive market for Trilaciclib dihydrochloride. Further, top-tier pharmaceutical companies intensify the competitive landscape, continually seeking approvals for new applications of Trilaciclib dihydrochloride from the FDA, driving growth. Sponsoring clinical trials and promoting research and development activities provide additional momentum. However, stringent regulations and patent cliffs pose challenges.

Asia-Pacific Outlook

The Asia-Pacific region is experiencing accelerated growth in the Trilaciclib dihydrochloride market. This progression is due to the regions burgeoning population, rising disposable income, and increasing healthcare investment. Nations such as China and India present immense potential, with escalating incidences of cancer and substantial growth in medical tourism. Increasing government initiatives to improve healthcare services, combined with emerging pharmaceutical manufacturers, stimulate the market further. However, patent infringement issues and imitation drugs create significant competition and act as potential roadblocks. The regions growth is also driven by its growing pharmaceutical exports, supplementing the global availability of Trilaciclib dihydrochloride.

Growth Opportunities in North America and Asia-Pacific

Established and Emerging Market's Growth Trend 2025–2034

1

Major Markets : U.S., Germany, UK, Japan, China are expected to grow at 4.5% to 6.7% CAGR

2

Emerging Markets : Brazil, India, South Africa are expected to grow at 8.0% to 9.7% CAGR

Market Analysis Chart

Analyzing the global market landscape, it is evident that the key market drivers for Trilaciclib dihydrochloride include the rising prevalence of various hematologic malignancies and broader recognition of its therapeutic potential. Its remarkable efficacy, especially in decreasing the occurrence of chemotherapy-induced myelosuppression, significantly reinforces market growth.

Recent Developments and Technological Advancement

December 2024

Acquisition of Novartis, a Swiss multinational pharmaceutical company, by Medivir AB, a Swedish biopharmaceutical revolving around Trilaciclib dihydrochloride patent rights

November 2024

Launch of an advanced version of Trilaciclib dihydrochloride by Amgen, an American multinational biopharmaceutical company, featuring improved dosage forms and better patient adherence

September 2024

Approval granted by the Food and Drug Administration for Eli Lillys innovative Trilaciclib dihydrochloride-based therapy for aggressive forms of cancer.

Trilaciclib dihydrochloride has emerged as a highly favored subject in the pharmaceutical research sector, with its unique applications in the oncology field gaining significant traction. Recent developments in this market are showing promising forward strides, primarily driven by advancements in cancer treatments and supportive care therapies.

Impact of Industry Transitions on the Trilaciclib Dihydrochloride Market

As a core segment of the Pharmaceutical industry, the Trilaciclib Dihydrochloride market develops in line with broader industry shifts. Over recent years, transitions such as Oncological Treatment Advancements and Pharma R&D Implications have redefined priorities across the Pharmaceutical sector, influencing how the Trilaciclib Dihydrochloride market evolves in terms of demand, applications and competitive dynamics. These transitions highlight the structural changes shaping long-term growth opportunities.

1

Oncological Treatment Advancements:

Trilaciclib dihydrochloride has emerged as innovative cancer treatment, posing meaningful impacts within the oncology sector. This compound has extraordinary potential in regulating cell cycle progression, protecting bone marrow from the damaging effects of chemotherapy. The adoption of Trilaciclib dihydrochloride has fostered the development of new therapies, facilitating enhanced patient outcomes and expanded possibilities for medical professionals in the oncology field.

2

Pharma R&D Implications:

A second transition catalyzed by Trilaciclib dihydrochloride relates to the pharmaceuticalindustry'sresearch and development segment. Its discovery has triggered a new realm of research in cancer therapy, encouraging trials and studies around the world. Pharmaceutical companies are leveraging its potential to create more effective, patientfriendly treatment options. Hence, Trilaciclib dihydrochloride has not only changed the scope of treatment but also the direction of pharmaceutical research.

Global Events Shaping Future Growth

The chart below highlights how external events including emerging market developments, regulatory changes, and technological disruptions, have added another layer of complexity to the Pharmaceutical industry. These events have disrupted supply networks, changed consumption behavior, and reshaped growth patterns. Together with structural industry transitions, they demonstrate how changes within the Pharmaceutical industry cascade into the Trilaciclib Dihydrochloride market, setting the stage for its future growth trajectory.

Market Dynamics and Supply Chain

Driver: Increasing Prevalence of Cancer, and Favorable Drug Approvals and Regulations

Recent years have also observed a significant rise in the number of cancer patients across the globe. As a potent inhibitor of CDK4 and CDK6 proteins, Trilaciclib dihydrochloride has also shown promising results in clinical trials against severals of cancer including small cell lung cancer and breast cancer. This rising prevalence certainly leads towards the increased adoption of advanced therapies and treatments, acting as a significant growth driving factor for the Trilaciclib dihydrochloride market.
Rigorous research and an array of successful clinical trials have also led regulatory bodies like the U. S. Food and Drug Administration to grant Breakthrough Therapy Designation to Trilaciclib for patients with extensive-stage SCLC.
The pharmaceutical industry is also experiencing significant technological advancements in the development of novel drugs for serious health conditions. Precision medicine and targeted therapies are also a focal point of these developments. Trilaciclib dihydrochloride, proven to protect the immune system during chemotherapy, has also earned recognition due to its targeted approach. This inclination towards personalized treatments is also further driving the demand for Trilaciclib dihydrochloride, spurring its market growth.

Restraint: Regulatory Hurdles

The rigorous regulatory standards for pharmaceutical products are a crucial factor impeding the growth of the Trilaciclib dihydrochloride market. This compound, used in cancer treatment, requires approval from bodies like the FDA, EMA, and others before it can be sold in any market. The approval process sometimes lasts multiple years and requires substantial research documentation, which delays the products access to the market, thereby restraining the market demand and dynamics.

Challenge: High Research and Development Costs

Developing a pharmaceutical product like Trilaciclib dihydrochloride requires significant financial input. The compounds research and development phase is time-consuming and costly, encompassing in-depth clinical trials to establish its safety and efficacy. Companies willing to produce and distribute this compound must prepare for high initial investment costs, which could potentially limit the entry of new players into the market, thus impacting market demand and dynamics.

Supply Chain Landscape

Raw Material Procurement

BASF

Dow Chemicals

Synthesis

Merck

Boehringer Ingelheim

Formulation & Packaging
G1 Therapeutics / Bayer Pharmaceuticals
Distribution & Retail
McKesson Corporation / AmerisourceBergen Corporation
Raw Material Procurement

BASF

Dow Chemicals

Synthesis

Merck

Boehringer Ingelheim

Formulation & Packaging

G1 Therapeutics

Bayer Pharmaceuticals

Distribution & Retail

McKesson Corporation

AmerisourceBergen Corporation

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Leading Providers and Their Strategies

Application AreaIndustryLeading Providers / ConsumersProvider Strategies
Cancer Therapy
Medical & Healthcare
G1 Therapeutics
Focuses on modern approaches to guard healthy cells from the harm caused by chemotherapy with Trilaciclib dihydrochloride
Chemotherapy-induced Myelosuppression Prevention
Pharmaceutical
EQRx, Inc.
Use of Trilaciclib dihydrochloride to lessen the occurrence of myelosuppression, thus increasing the effectiveness of chemotherapy
Small Cell Lung Cancer Treatment
Biotechnology
Boehringer Ingelheim
Concentrates on the use of Trilaciclib dihydrochloride as a protective agent for bone marrow during chemotherapy treatment

Elevate your strategic vision with in-depth analysis of key applications, leading market players, and their strategies. The report analyzes industry leaders' views and statements on the Trilaciclib Dihydrochloride market's present and future growth.

Our research is created following strict editorial standards. See our Editorial Policy

Applications of Trilaciclib Dihydrochloride in Oncology Treatment and Hematopoiesis Preservation

Oncology Treatment

Trilaciclib dihydrochloride is predominantly used in the field of oncology, showing spectacular outcomes in cancer treatment. Small molecule inhibitors like Trilaciclib dihydrochloride intervene with the process of mitosis, preventing cancer cells from replicating. The unique advantage of Trilaciclib dihydrochloride is its capacity to shield healthy cells from chemotherapy-induced damage, thus improving the patients quality of life during treatment. G1 Therapeutics, a well-established player in this field, has strengthened its market position by developing innovative therapies utilizing Trilaciclib dihydrochloride.

Hematopoiesis Preservation

Another wide application of Trilaciclib dihydrochloride can be seen in preserving hematopoiesis the process of blood cell production. This application primarily uses serine/threonine-protein kinase inhibitors, which Trilaciclib dihydrochloride belongs to. These compounds protect bone marrow cells from damage during chemotherapy, promoting faster recovery and minimizing risks like anemia or infections. Also in this space, leading pharmaceutical companies such as G1 Therapeutics have redefined hematopoiesis preservation, enhancing overall treatments with improved application of Trilaciclib dihydrochloride.

Trilaciclib Dihydrochloride vs. Substitutes:
Performance and Positioning Analysis

Trilaciclib dihydrochloride distinguishes itself by its unique mechanism of action and its potentialities in combating chemotherapy-induced myelosuppression, projecting noticeable growth in the pharmaceutical sector. Whereas alternatives lack such specific therapeutic focus

Trilaciclib Dihydrochloride
  • Palladia /
  • Gleevec /
  • Nexavar
    Effective in protecting the immune system during chemotherapy, Potential to improve patient outcomes
    Limited data from clinical trials, High cost of treatment
    Effective in inhibiting tumor growth, broad spectrum antitumor activity
    High toxicity, side effects such as nausea and hair loss

Trilaciclib Dihydrochloride vs. Substitutes:
Performance and Positioning Analysis

Trilaciclib Dihydrochloride

  • Effective in protecting the immune system during chemotherapy, Potential to improve patient outcomes
  • Limited data from clinical trials, High cost of treatment

Palladia / Gleevec / Nexavar

  • Effective in inhibiting tumor growth, broad spectrum antitumor activity
  • High toxicity, side effects such as nausea and hair loss

Trilaciclib dihydrochloride distinguishes itself by its unique mechanism of action and its potentialities in combating chemotherapy-induced myelosuppression, projecting noticeable growth in the pharmaceutical sector. Whereas alternatives lack such specific therapeutic focus

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Research Methodology

This market research methodology defines the Trilaciclib Dihydrochloride market scope, gathers reliable data, and validates findings using integrated primary and secondary research. Our systematic framework ensures precise market sizing, growth trend analysis, and competitive benchmarking.


Secondary Research Approach


We begin secondary research by defining the targeted market at Country and Regional levels. As part of the Pharmaceutical ecosystem, we analyze Trilaciclib Dihydrochloride across Chemotherapy-Induced Myelosuppression Prevention, Small Cell Lung Cancer Treatment, and Metastatic Triple-Negative Breast Cancer Treatment Applications. Our team gathers data systematically from country level ministerial sources, industry associations & federations, trade databases, company annual & quarterly reports and other credential sources, enabling us to map global and regional market size, pricing trends, regulatory standards, and technology advancements.


Key Sources Referenced:


We benchmark competitors such as G1 Therapeutics, Hengrui Medicine, and Zydus Cadila by reviewing company financial statements, and regulatory filings. Our secondary insights identify key market drivers and constraints, forming the analytical foundation for primary research.


Primary Research Methods


We conduct structured interviews and surveys with industry stakeholders, including Raw Material Procurement, Synthesis, and Formulation & Packaging. Our geographic coverage spans Americas (40%), Europe (30%), Asia-Pacific (25%) and Middle East & Africa (5%). Our online surveys generally achieve a response rate of above 65%, and telephone interviews yield 60%, resulting in above 92% confidence level with a ±7% margin of error.


Through targeted questionnaires and in-depth interviews, we capture purchase intent, adoption barriers, brand perception across Segment Type. We use interview guides to ensure consistency and anonymous survey options to mitigate response bias. These primary insights validate secondary findings and align market sizing with real-world conditions.


Market Engineering & Data Analysis Framework


Our data analysis framework integrates Top-Down, Bottom-Up, and Company Market Share approaches to estimate and project market size with precision.


Top-down & Bottom-Up Process


In Top-down approach, we disaggregate global Pharmaceutical revenues to estimate the Trilaciclib Dihydrochloride segment, using historical growth patterns to set baseline trends. Simultaneously, in Bottom-up approach, we aggregate Country-Level Demand Data to derive regional and global forecasts, which provide granular consumption insights. By reconciling both approaches, we ensure statistical precision and cross-validation accuracy.


We evaluate the supply chain, spanning Raw Material Procurement (BASF, Dow Chemicals), Synthesis (Merck, Boehringer Ingelheim), and Formulation & Packaging. Our parallel substitute analysis examines Palladia, Gleevec, and Nexavar, highlighting diversification opportunities and competitive risks.


Company Market Share & Benchmarking


We benchmark leading companies such as G1 Therapeutics, Hengrui Medicine, and Zydus Cadila, analyzing their capabilities in pricing, product features, technology adoption, and distribution reach. By assessing company-level revenues and product portfolios, we derive market share comparisons, clarifying competitive positioning and growth trajectories across the ecosystem.


Our integration of data triangulation, supply chain evaluation, and company benchmarking, supported by our proprietary Directional Superposition methodology enables us to deliver precise forecasts and actionable strategic insights into the Trilaciclib Dihydrochloride market.


Quality Assurance and Compliance


We cross-reference secondary data with primary inputs and external expert reviews to confirm consistency. Further, we use stratified sampling, anonymous surveys, third-party interviews, and time-based sampling to reduce bias and strengthen our results.


Our methodology is developed in alignment with ISO 20252 standards and ICC/ESOMAR guidelines for research ethics. The study methodology follows globally recognized frameworks such as ISO 20252 and ICC codes of practice.

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Trilaciclib Dihydrochloride Market Data: Size, Segmentation & Growth Forecast

Report AttributeDetails
Market Value in 2025USD 702 million
Revenue Forecast in 2034USD 1.29 billion
Growth RateCAGR of 7.0% from 2025 to 2034
Base Year for Estimation2024
Industry Revenue 2024656 million
Growth OpportunityUSD 635 million
Historical Data2019 - 2023
Growth Projection / Forecast Period2025 - 2034
Market Size UnitsMarket Revenue in USD million and Industry Statistics
Market Size 2024656 million USD
Market Size 2027804 million USD
Market Size 2029921 million USD
Market Size 2030985 million USD
Market Size 20341.29 billion USD
Market Size 20351.38 billion USD
Report CoverageMarket revenue for past 5 years and forecast for future 10 years, Competitive Analysis & Company Market Share, Strategic Insights & trends
Segments CoveredProduct Form, Applications, Distribution Channel, Possible Combinations
Regional scopeNorth America, Europe, Asia Pacific, Latin America and Middle East & Africa
Country scopeU.S., Canada, Mexico, UK, Germany, France, Italy, Spain, China, India, Japan, South Korea, Brazil, Mexico, Argentina, Saudi Arabia, UAE and South Africa
Companies ProfiledG1 Therapeutics, Hengrui Medicine, Zydus Cadila, Torrent Pharma, Glenmark Pharmaceuticals, Sun Pharma Advanced Research Company, Pfizer, AstraZeneca, AbbVie, Merck, Roche and Novartis
CustomizationFree customization at segment, region or country scope and direct contact with report analyst team for 10 to 20 working hours for any additional niche requirement which is almost equivalent to 10% of report value

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Table of Contents

Industry Insights Report - Table Of Contents

Chapter 1

Executive Summary

Major Markets & Their Performance - Statistical Snapshots

Chapter 2

Research Methodology

2.1Axioms & Postulates
2.2Market Introduction & Research MethodologyEstimation & Forecast Parameters / Major Databases & Sources
Chapter 3

Market Dynamics

3.1Market OverviewDrivers / Restraints / Opportunities / M4 Factors
3.2Market Trends
3.2.1Introduction & Narratives
3.2.2Market Trends - Impact Analysis(Short, Medium & Long Term Impacts)
3.3Supply Chain Analysis
3.4Porter's Five ForcesSuppliers & Buyers' Bargaining Power, Threat of Substitution & New Market Entrants, Competitive Rivalry
Chapter 4

Trilaciclib Dihydrochloride Market Size, Opportunities & Strategic Insights, by Product Form

4.1Intravenous Solution
4.2Tablet
Chapter 5

Trilaciclib Dihydrochloride Market Size, Opportunities & Strategic Insights, by Applications

5.1Chemotherapy-Induced Myelosuppression Prevention
5.2Small Cell Lung Cancer Treatment
5.3Metastatic Triple-Negative Breast Cancer Treatment
5.4Others
Chapter 6

Trilaciclib Dihydrochloride Market Size, Opportunities & Strategic Insights, by Distribution Channel

6.1Hospital Pharmacies
6.2Retail Pharmacies
6.3Online Pharmacies
Chapter 7

Trilaciclib Dihydrochloride Market Size, Opportunities & Strategic Insights, by Possible Combinations

7.1Monotherapy
7.2Combination Therapy
Chapter 8

Trilaciclib Dihydrochloride Market, by Region

8.1North America Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.1.1U.S.
8.1.2Canada
8.2Europe Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.2.1Germany
8.2.2France
8.2.3UK
8.2.4Italy
8.2.5The Netherlands
8.2.6Rest of EU
8.3Asia Pacific Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.3.1China
8.3.2Japan
8.3.3South Korea
8.3.4India
8.3.5Australia
8.3.6Thailand
8.3.7Rest of APAC
8.4Middle East & Africa Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.4.1Saudi Arabia
8.4.2United Arab Emirates
8.4.3South Africa
8.4.4Rest of MEA
8.5Latin America Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.5.1Brazil
8.5.2Mexico
8.5.3Rest of LA
8.6CIS Trilaciclib Dihydrochloride Market Size, Opportunities, Key Trends & Strategic Insights
8.6.1Russia
8.6.2Rest of CIS
Chapter 9

Competitive Landscape

9.1Competitive Dashboard & Market Share Analysis
9.2Company Profiles (Overview, Financials, Developments, SWOT)
9.2.1G1 Therapeutics
9.2.2Hengrui Medicine
9.2.3Zydus Cadila
9.2.4Torrent Pharma
9.2.5Glenmark Pharmaceuticals
9.2.6Sun Pharma Advanced Research Company
9.2.7Pfizer
9.2.8AstraZeneca
9.2.9AbbVie
9.2.10Merck
9.2.11Roche
9.2.12Novartis