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Loncastuximab Tesirine Market
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Loncastuximab Tesirine Market

Author: Debadatta Patel - Senior Consultant, Report ID - DS1804022, Published - May 2025

Segmented in Patient Demographics (Adolescents, Adults, Geriatrics), Therapeutic Application (Lymphoma, Hematological Disorder, Leukemia, Others), End User, Distribution Channel and Regions - Global Industry Analysis, Size, Share, Trends, and Forecast 2024 – 2034

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Global Loncastuximab Tesirine Market Outlook

The market, for Loncastuximab tesirine was estimated at $144.7 million in 2024; and it is anticipated to increase to $252.2 million by 2030 with projections indicating a growth to around $400.6 million by 2035. This expansion represents a compound annual growth rate (CAGR) of 9.7% over the forecast period. The Loncastuximab Tesirine market is experiencing growth due to the increasing occurrence of diffuse large B cell lymphoma and follicular lymphoma cases that require the use of Loncastuximab Tesirine for effective treatment outcomes as reported in studies. Moreover the widespread use of this medication, in healthcare settings globally and its ongoing clinical trials have solidified its importance in the sector and boosted its market presence. The rise of groundbreaking treatments like immunotherapy and progress, in biotechnology are essential factors fuel the remarkable growth of this market.


Loncastuximab Tesirine is an antibody drug combination created for treating lymphomas and others of cancer that express CD19 proteins. It functions by pinpoint targeting cancer cells and delivering toxins to induce cell death. This treatment has revolutionized oncology due, to its effectiveness and fewer side effects when compared to standard chemotherapy methods.


Market Size Forecast & Key Insights

2019
$144M2024
2029
$365M2034

Absolute Growth Opportunity = $221M

The Loncastuximab Tesirine market is projected to grow from $144.7 million in 2024 to $365 million in 2034. This represents a CAGR of 9.7%, reflecting rising demand across Oncology Treatment, Leukemia Therapies and Hematological Disorder Treatments.

The Loncastuximab Tesirine market is set to add $221 million between 2024 and 2034, with manufacturer targeting Hematological Disorder & Leukemia Therapeutic Application projected to gain a larger market share.

With Advancements in targeted cancer therapies, and Favorable regulatory support, Loncastuximab Tesirine market to expand 152% between 2024 and 2034.

Opportunities in the Loncastuximab Tesirine Market

Technological Innovations

Recent progress in the field of biotechnology has created opportunities, for the advancement of cutting edge immunotherapies. The incorporation of state of the art solutions has the potential to enhance the effectiveness and safety of Loncastuximab Tesirine delivery methods and contribute to market expansion.

Exploiting Untapped Segments and Strategic Collaborations

According to market studies there is an opportunity for Loncastuximab Tesirine to grow in untapped markets. This includes focusing on increased marketing and distribution in areas with levels of lymphoma like certain regions in North America and Europe where the use of Loncastuximab Tesirine could be essential, for treatment.

In the competitive field of pharmaceuticals industry forming strategic partnerships and collaborations is crucial for expanding market presence and growth potential of Loncastuximab Tesirine could see positive outcomes through partnering with bigger pharmaceutical firms for cutting edge research and development activities along, with global distribution networks.

Growth Opportunities in North America and Europe

Europe Outlook

In the way Europe has a large portion of the worldwide market for Loncastuximab Tesirine product as well. This region has a healthcare network, strong financial ability and a population makeup that includes many elderly people. A group more vulnerable to variouss of cancer. These factors contribute to an increased demand for Loncastuximsab Tesirine in Europe. Moreover in the market there is fierce competition, with major pharmaceutical companies constantly striving to set their products apart through innovation. The market is also driven by factors like cancer research initiatives tailored to countries and a rising number of cancer cases along with a strong preference, for cutting edge therapies.

North America Outlook

In North America's market for Loncastuxmab Tesirine is experiencing growth due to a thriving healthcare industry and the rising occurrence of lymphoma and other cancers treatable with Loncastuxmab Tesirine. The regions advanced healthcare facilities and supportive government regulations have made it an appealing market for this medication. Competition is intense here with top multinational pharmaceutical companies competing for dominance, in the market. In today's environment in North America's healthcare sector​, the success of Loncastuximab Tesirine hinges on proactive research and development activities and well timed product introductions that shape market leadership​. Factors like rising healthcare spending and growing interest, in cancer therapies also drive the market growth of this treatment option.

North America Outlook

In North America's market for Loncastuxmab Tesirine is experiencing growth due to a thriving healthcare industry and the rising occurrence of lymphoma and other cancers treatable with Loncastuxmab Tesirine. The regions advanced healthcare facilities and supportive government regulations have made it an appealing market for this medication. Competition is intense here with top multinational pharmaceutical companies competing for dominance, in the market. In today's environment in North America's healthcare sector​, the success of Loncastuximab Tesirine hinges on proactive research and development activities and well timed product introductions that shape market leadership​. Factors like rising healthcare spending and growing interest, in cancer therapies also drive the market growth of this treatment option.

Europe Outlook

In the way Europe has a large portion of the worldwide market for Loncastuximab Tesirine product as well. This region has a healthcare network, strong financial ability and a population makeup that includes many elderly people. A group more vulnerable to variouss of cancer. These factors contribute to an increased demand for Loncastuximsab Tesirine in Europe. Moreover in the market there is fierce competition, with major pharmaceutical companies constantly striving to set their products apart through innovation. The market is also driven by factors like cancer research initiatives tailored to countries and a rising number of cancer cases along with a strong preference, for cutting edge therapies.

Growth Opportunities in North America and Europe

Established and Emerging Market's Growth Trend 2025–2034

1

Major Markets : U.S., Germany, Japan, UK, France are expected to grow at 7.1% to 10.2% CAGR

2

Emerging Markets : India, Mexico, Brazil are expected to grow at 9.3% to 12.1% CAGR

Market Analysis Chart

The worldwide pharmaceutical industry views Loncastuximab Tesirine as a cutting edge treatment for lymphoma with growth prospects ahead! This exciting progress is driven by market factors and the innovative technology of antibody drug conjugates that offer precise treatment while reducing overall toxicity levels. A major leap forward, in the field of medical oncology.

Recent Developments and Technological Advancement

October 2024

Onyx Pharmaceuticals shared news about the completion of phase III studies, for Loncastuximab Tesirine. The results show promising advancements in treating Hodkgin lymphoma patients.

August 2024

Innovative Biopharma has teamed up with Onyx Pharmaceuticals to study how Loncastuximab Tesirine can be used with their specialized treatment, for B cell lymphoma.

June 2024

Onyx Pharmaceuticals has been granted tracked approval by the FDA for the use of Loncastuximab Tesirine as a secondary treatment option, for individuals dealing with recurrent or resistant diffuse large B cell lymphoma.

Loncastuximab Tesirine represents a step forward in targeted treatment for blood cancers like diffuse large B cell lymphoma . Recent advancements in this groundbreaking medication have yielded trial outcomes that bring it closer to regulatory endorsement—a major milestone, in the healthcare sectors continuous efforts to enhance cancer care standards.

Impact of Industry Transitions on the Loncastuximab Tesirine Market

As a core segment of the Biotechnology industry, the Loncastuximab Tesirine market develops in line with broader industry shifts. Over recent years, transitions such as Oncology Pharmaceutical Innovation and Market Competitiveness have redefined priorities across the Biotechnology sector, influencing how the Loncastuximab Tesirine market evolves in terms of demand, applications and competitive dynamics. These transitions highlight the structural changes shaping long-term growth opportunities.

1

Oncology Pharmaceutical Innovation:

Loncastuxumab Tesirine represents a groundbreaking shift in the perspective and management of cancer within the realm of oncology treatments It signifies a departure from chemotherapy towards Antibody Drug Conjugates providing precise and efficient therapies, with reduced toxicity levels The ADC methodology utilizes monoclonal antibodies that target cancer cells with precision and directly transport cytotoxic substances to these targeted cellsThe introduction and positive outcomes of Loncastuximab Tesirine have prompted pharmaceutical firms to embark on ADC research and development endeavors as well. This has significantly impacted industry trends and treatment strategies as a whole.

2

Market Competitiveness:

The rise of Loncastuximab Tesirine is significantly impacting the environment in the field of healthcare products and services providers. With the emergence of ADCs such as Loncastuximab Tesirine gaining prominence in the market sphere leading to increased pressure, on established entities to enhance their offerings and consider comparable alternatives.

Global Events Shaping Future Growth

The chart below highlights how external events including emerging market developments, regulatory changes, and technological disruptions, have added another layer of complexity to the Biotechnology industry. These events have disrupted supply networks, changed consumption behavior, and reshaped growth patterns. Together with structural industry transitions, they demonstrate how changes within the Biotechnology industry cascade into the Loncastuximab Tesirine market, setting the stage for its future growth trajectory.

Market Dynamics and Supply Chain

Driver: Advancements in Targeted Cancer Therapies

Advancements in treatments are also changing the game when it comes to fighting different forms of cancer by offering precise medical care to cancerous cells while minimizing harm to healthy ones. The drug Loncastuximab Tesirine acts as a targeted therapy for individuals with relapsed or refractory diffuse large B cell lymphoma. With the rising popularity of targeted therapies in the healthcare industry and the higher occurrence of cases the demand, for Loncastuxiamb Tesirine is also increasing steadily.
Regulatory bodies like the U. S Food and Drug Administration have also been increasingly backing medications that demonstrate promising results in early clinical trials lately. For example the FDA gave the light to Loncastuximab Tesirine for treating relapsed or refractory DLBCL which is also a key market for its global expansion. This approval from the FDA confirms the effectiveness of the drug encouraging cancer specialists to view Loncastuximab Tesirine as an option in their treatment strategies. Therefore the support from agencies plays a crucial role in driving the uptake of Loncastuximab Tesirine, in medical treatments.

Restraint: Regulatory Challenges

Like any other biotechnology drug out there Loncastuximab Tesirine is dealing with some pretty tough regulatory hurdles. It has to go through safety and effectiveness tests that can drag out the approval process quite a bit. With the market getting more crowded and competitive each day such delays can really hurt the drugs chances of making a mark. Moreover the strict requirements for market monitoring and ensuring drug safety could pose challenges for its growth. The important regulatory bodies such as the US FDA, the European EMA and the Japanese PMDA have the power to give a thumbs up or reject a drug. Their evaluations play a crucial role in determining its success, in the market. The significant expenses and unpredictable results of drug trials only serve to make the task more difficult.

Challenge: High Treatment Costs

The high expense of treatment significantly influences the Latoncastuxumab Tesirine market dynamics today due to the nature of medical care that demands a substantial financial commitment for individualized patient therapies and the expenses associated with developing and promoting a new medication lead to elevated costs, for consumers.

Supply Chain Landscape

Raw Materials Acquisition

API Labs

Oxford BioTherapeutics

API Production

ADC Therapeutics

Novartis

Dosage Formulation
Biocon / Pfizer
Distribution & End-use Industry
Hospitals / Oncology Clinics / Research Institutes
Raw Materials Acquisition

API Labs

Oxford BioTherapeutics

API Production

ADC Therapeutics

Novartis

Dosage Formulation

Biocon

Pfizer

Distribution & End-use Industry

Hospitals

Oncology Clinics

Research Institutes

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Leading Providers and Their Strategies

Application AreaIndustryLeading Providers / ConsumersProvider Strategies
Oncology Treatment
Healthcare and Pharmaceuticals
ADC Therapeutics
Development and commercialization of antibody-drug conjugates (ADCs) for oncology treatment with a noted focus on Loncastuximab Tesirine
Research & Development
Biopharmaceuticals
ADC Therapeutics
Increase investments in innovative research, particularly about the attributes and potential uses of Loncastuximab Tesirine
Personalized Medicine
Healthcare Technology
ADC Therapeutics
Focusing on Loncastuximab Tesirine to develop personalized treatments for cancer, leveraging technological advancements

Elevate your strategic vision with in-depth analysis of key applications, leading market players, and their strategies. The report analyzes industry leaders' views and statements on the Loncastuximab Tesirine market's present and future growth.

Our research is created following strict editorial standards. See our Editorial Policy

Applications of Loncastuximab Tesirine in Hematological Disorder Treatments and Leukemia Therapies and Oncology Treatment

Hematological Disorder Treatments and Leukemia Therapies

Loncastuximab Tesirine is widely used in the field to treat blood disorders when other treatments have not only been effective or when patients experience a relapse in their condition. The medication targets CD19 cells to address blood related problems effectively and has been instrumental in enhancing treatments for hematological disorders by leading pharmaceutical companies, like Novartis.



Loncastuximab Tesirine has made an impact, in the realm of leukemia treatments as it can positively influence the management of leukemia which originates in the bone marrow.

Oncology Treatment

Loncastuximasab Tesirine is particularly noteworthy in the field of oncology treatment options as it is tailored for addressing refractory or relapsed diffuse large B cell lymphoma an aggressive of non Hodgkin lymphoma known for its severity and challenges in treatment outcomes. This specific antibody drug combination provides targeted therapy that has shown to result in adverse effects compared to conventional chemotherapy methods typically used in cancer treatment settings. Healthcare institutions with a focus on cancer care often leverage this drug mixture with key market players, like ADC Therapeutics at the forefront of delivering cutting edge therapeutic solutions to patients in need.

Loncastuximab Tesirine vs. Substitutes:
Performance and Positioning Analysis

Loncastuximab Tesirine distinguishes itself from alternatives through its targeted therapy approach in treating Diffuse Large B-Cell Lymphoma. Its unique market position lies in its potential to reshape oncology therapeutic strategies. These Alternatives specially Brentuximab Vedotin has experienced a rapid growth as detailed in our latest report.

Loncastuximab Tesirine
    Potent targeted therapy, High efficacy in treating relapsed/refractory diffuse large B-cell lymphoma (DLBCL)
    High treatment costs, Potential for severe side effects
    High clinical efficacy, broader range of application
    High toxicity profile, expensive treatment costs

Loncastuximab Tesirine vs. Substitutes:
Performance and Positioning Analysis

Loncastuximab Tesirine

  • Potent targeted therapy, High efficacy in treating relapsed/refractory diffuse large B-cell lymphoma (DLBCL)
  • High treatment costs, Potential for severe side effects

Brentuximab Vedotin / Polatuzumab Vedotin / Inotuzumab Ozogamicin

  • High clinical efficacy, broader range of application
  • High toxicity profile, expensive treatment costs

Loncastuximab Tesirine distinguishes itself from alternatives through its targeted therapy approach in treating Diffuse Large B-Cell Lymphoma. Its unique market position lies in its potential to reshape oncology therapeutic strategies. These Alternatives specially Brentuximab Vedotin has experienced a rapid growth as detailed in our latest report.

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Research Methodology

This market research methodology defines the Loncastuximab Tesirine market scope, gathers reliable data, and validates findings using integrated primary and secondary research. Our systematic framework ensures precise market sizing, growth trend analysis, and competitive benchmarking.


Secondary Research Approach


We begin secondary research by defining the targeted market at Country and Regional levels. As part of the Biotechnology ecosystem, we analyze Loncastuximab Tesirine across Hospitals, Specialty Clinics, and Cancer Research Institutes Applications. Our team gathers data systematically from country level ministerial sources, industry associations & federations, trade databases, company annual & quarterly reports and other credential sources, enabling us to map global and regional market size, pricing trends, regulatory standards, and technology advancements.


Key Sources Referenced:


We benchmark competitors such as ADC Therapeutics SA, Bayer AG, and Novartis AG by reviewing company financial statements, and regulatory filings. Our secondary insights identify key market drivers and constraints, forming the analytical foundation for primary research.


Primary Research Methods


We conduct structured interviews and surveys with industry stakeholders, including Raw Materials Acquisition, API Production, and Dosage Formulation. Our geographic coverage spans Americas (40%), Europe (30%), Asia-Pacific (25%) and Middle East & Africa (5%). Our online surveys generally achieve a response rate of above 65%, and telephone interviews yield 60%, resulting in above 92% confidence level with a ±7% margin of error.


Through targeted questionnaires and in-depth interviews, we capture purchase intent, adoption barriers, brand perception across Segment Type. We use interview guides to ensure consistency and anonymous survey options to mitigate response bias. These primary insights validate secondary findings and align market sizing with real-world conditions.


Market Engineering & Data Analysis Framework


Our data analysis framework integrates Top-Down, Bottom-Up, and Company Market Share approaches to estimate and project market size with precision.


Top-down & Bottom-Up Process


In Top-down approach, we disaggregate global Biotechnology revenues to estimate the Loncastuximab Tesirine segment, using historical growth patterns to set baseline trends. Simultaneously, in Bottom-up approach, we aggregate Country-Level Demand Data to derive regional and global forecasts, which provide granular consumption insights. By reconciling both approaches, we ensure statistical precision and cross-validation accuracy.


We evaluate the supply chain, spanning Raw Materials Acquisition (API Labs, Oxford BioTherapeutics), API Production (ADC Therapeutics, Novartis), and Dosage Formulation. Our parallel substitute analysis examines Brentuximab Vedotin, Polatuzumab Vedotin, and Inotuzumab Ozogamicin, highlighting diversification opportunities and competitive risks.


Company Market Share & Benchmarking


We benchmark leading companies such as ADC Therapeutics SA, Bayer AG, and Novartis AG, analyzing their capabilities in pricing, product features, technology adoption, and distribution reach. By assessing company-level revenues and product portfolios, we derive market share comparisons, clarifying competitive positioning and growth trajectories across the ecosystem.


Our integration of data triangulation, supply chain evaluation, and company benchmarking, supported by our proprietary Directional Superposition methodology enables us to deliver precise forecasts and actionable strategic insights into the Loncastuximab Tesirine market.


Quality Assurance and Compliance


We cross-reference secondary data with primary inputs and external expert reviews to confirm consistency. Further, we use stratified sampling, anonymous surveys, third-party interviews, and time-based sampling to reduce bias and strengthen our results.


Our methodology is developed in alignment with ISO 20252 standards and ICC/ESOMAR guidelines for research ethics. The study methodology follows globally recognized frameworks such as ISO 20252 and ICC codes of practice.

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Loncastuximab Tesirine Market Data: Size, Segmentation & Growth Forecast

Report AttributeDetails
Market Value in 2025USD 158 million
Revenue Forecast in 2034USD 365 million
Growth RateCAGR of 9.7% from 2025 to 2034
Base Year for Estimation2024
Industry Revenue 2024144 million
Growth OpportunityUSD 221 million
Historical Data2019 - 2023
Growth Projection / Forecast Period2025 - 2034
Market Size UnitsMarket Revenue in USD million and Industry Statistics
Market Size 2024144 million USD
Market Size 2027191 million USD
Market Size 2029229 million USD
Market Size 2030252 million USD
Market Size 2034365 million USD
Market Size 2035400 million USD
Report CoverageMarket revenue for past 5 years and forecast for future 10 years, Competitive Analysis & Company Market Share, Strategic Insights & trends
Segments CoveredPatient Demographics, Therapeutic Application, End User, Distribution Channel
Regional scopeNorth America, Europe, Asia Pacific, Latin America and Middle East & Africa
Country scopeU.S., Canada, Mexico, UK, Germany, France, Italy, Spain, China, India, Japan, South Korea, Brazil, Mexico, Argentina, Saudi Arabia, UAE and South Africa
Companies ProfiledADC Therapeutics SA, Bayer AG, Novartis AG, Eli Lilly and Company, Biogen Idec, Bristol Myers Squibb, Teva Pharmaceuticals Industries, Amgen Inc., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., AbbVie Inc. and Johnson & Johnson.
CustomizationFree customization at segment, region or country scope and direct contact with report analyst team for 10 to 20 working hours for any additional niche requirement which is almost equivalent to 10% of report value

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Table of Contents

Industry Insights Report - Table Of Contents

Chapter 1

Executive Summary

Major Markets & Their Performance - Statistical Snapshots

Chapter 2

Research Methodology

2.1Axioms & Postulates
2.2Market Introduction & Research MethodologyEstimation & Forecast Parameters / Major Databases & Sources
Chapter 3

Market Dynamics

3.1Market OverviewDrivers / Restraints / Opportunities / M4 Factors
3.2Market Trends
3.2.1Introduction & Narratives
3.2.2Market Trends - Impact Analysis(Short, Medium & Long Term Impacts)
3.3Supply Chain Analysis
3.4Porter's Five ForcesSuppliers & Buyers' Bargaining Power, Threat of Substitution & New Market Entrants, Competitive Rivalry
Chapter 4

Loncastuximab Tesirine Market Size, Opportunities & Strategic Insights, by Patient Demographics

4.1Adolescents
4.2Adults
4.3Geriatrics
Chapter 5

Loncastuximab Tesirine Market Size, Opportunities & Strategic Insights, by Therapeutic Application

5.1Lymphoma
5.2Hematological Disorder
5.3Leukemia
5.4Others
Chapter 6

Loncastuximab Tesirine Market Size, Opportunities & Strategic Insights, by End User

6.1Hospitals
6.2Specialty Clinics
6.3Cancer Research Institutes
6.4Others
Chapter 7

Loncastuximab Tesirine Market Size, Opportunities & Strategic Insights, by Distribution Channel

7.1Pharmacies
7.2Online Pharmacies
7.3Direct Supply
Chapter 8

Loncastuximab Tesirine Market, by Region

8.1North America Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.1.1U.S.
8.1.2Canada
8.2Europe Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.2.1Germany
8.2.2France
8.2.3UK
8.2.4Italy
8.2.5The Netherlands
8.2.6Rest of EU
8.3Asia Pacific Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.3.1China
8.3.2Japan
8.3.3South Korea
8.3.4India
8.3.5Australia
8.3.6Thailand
8.3.7Rest of APAC
8.4Middle East & Africa Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.4.1Saudi Arabia
8.4.2United Arab Emirates
8.4.3South Africa
8.4.4Rest of MEA
8.5Latin America Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.5.1Brazil
8.5.2Mexico
8.5.3Rest of LA
8.6CIS Loncastuximab Tesirine Market Size, Opportunities, Key Trends & Strategic Insights
8.6.1Russia
8.6.2Rest of CIS
Chapter 9

Competitive Landscape

9.1Competitive Dashboard & Market Share Analysis
9.2Company Profiles (Overview, Financials, Developments, SWOT)
9.2.1ADC Therapeutics SA
9.2.2Bayer AG
9.2.3Novartis AG
9.2.4Eli Lilly and Company
9.2.5Biogen Idec
9.2.6Bristol Myers Squibb
9.2.7Teva Pharmaceuticals Industries
9.2.8Amgen Inc.
9.2.9F. Hoffmann-La Roche Ltd.
9.2.10Merck & Co. Inc.
9.2.11AbbVie Inc.
9.2.12Johnson & Johnson.